SCHEMBL6777942

SCHEMBL6777942

NC(=O)CC[C@H](NC(=O)c1ccc(COc2cccnc2)cc1-c1ccccc1)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FNTA P49354 1/20 0.65
FNTB P49356 1/20 0.65
GPR132 Q9UNW8 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6772090 0.91 FNTA (0.79) FNTAFNTB
SCHEMBL6775656 0.89 FNTA (0.67) FNTAFNTBGPR132
SCHEMBL6775660 0.89 FNTA (0.67) FNTAFNTBGPR132
SCHEMBL6781863 0.88 FNTA (0.67) FNTAFNTBGPR132
SCHEMBL6781871 0.88 FNTA (0.67) FNTAFNTBGPR132
SCHEMBL6776314 0.87 FNTA (0.64) FNTAFNTBGPR132
SCHEMBL6781916 0.87 FNTA (0.66) FNTAFNTBGPR132
SCHEMBL6776309 0.87 FNTA (0.64) FNTAFNTBGPR132
SCHEMBL6771418 0.87 FNTA (0.84) FNTAFNTB
SCHEMBL6771420 0.87 FNTA (0.84) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020193596-A1 Inhibitors of protein isoprenyl transferases UNIVERSITY OF PITTSBURGH (US) 2002-12-19 US claimed
US-6693123-B2 (4-(3-PYRIDYLAMINOMETHYLENE)-2-PHENYLBENZOYL)-N -METHYLMETHIONINE, METHYL ESTER FOR EXAMPLE; RESTENOSIS, HYPERPLASIA UNIVERSITY OF PITTSBURGH 2004-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020193596-A1 Inhibitors of protein isoprenyl transferases LANCL1, FNTB, DHCR7 FNTA 20/4885FNTB 2/4885GPR132 3333/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.