Sugi Predict

Sugi Predict / Compounds / Morpholine

Morpholine

Morpholine

SCHEMBL6778555

C1COCCN1.CCn1cc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2cc(CN3CCC[C@@H]3[C@@H](O)c3ccccc3)sc21

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ KCNH2 Q12809 1/20 0.51
▸ F2 P00734 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6669518 0.94 KCNH2 (0.51) KCNH2
SCHEMBL6746030 0.94 KCNH2 (0.51) KCNH2
SCHEMBL6746063 0.89 KCNH2 (0.52) KCNH2
SCHEMBL6746056 0.89 KCNH2 (0.52) KCNH2
SCHEMBL6746088 0.89 KCNH2 (0.59) KCNH2
SCHEMBL6746095 0.89 KCNH2 (0.59) KCNH2
SCHEMBL6681321 0.88 KCNH2 (0.57) KCNH2F2
SCHEMBL6681328 0.88 KCNH2 (0.57) KCNH2F2
SCHEMBL6666016 0.86 KCNH2 (0.51) KCNH2
SCHEMBL6746136 0.86 KCNH2 (0.51) KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6831081-B2 Herpes virus including simplex types 1 and 2, varicella zoster, human cytomegalovirus, Epstein-Barr and human 6, 7 and 8 PHARMACIA & UPJOHN 2004-12-14 — — US claimed