Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6778791 | 1.00 | PDE5A (0.56) | PDE5APDE6C | |
| SCHEMBL6412825 | 0.80 | PDE5A (0.56) | PDE5A | |
| SCHEMBL6635064 | 0.80 | PDE5A (0.56) | PDE5A | |
| SCHEMBL6773422 | 0.78 | PDE5A (0.61) | PDE5A | |
| SCHEMBL6635060 | 0.76 | PDE5A (0.56) | PDE5A | |
| SCHEMBL6412821 | 0.76 | PDE5A (0.56) | PDE5A | |
| SCHEMBL6412773 | 0.71 | PDE5A (1.00) | PDE5A | |
| SCHEMBL6411846 | 0.66 | PDE5A (0.61) | PDE5A | |
| SCHEMBL6405906 | 0.66 | PDE5A (0.53) | PDE5APDE6C | |
| SCHEMBL6412618 | 0.66 | PDE5A (0.53) | PDE5APDE6C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6818646-B2 | 1,2,3,4-TETRAHYDRO-2-(5-(2-PYRIDINYL)-PYRIMIDIN-2-YL)-3-(2,3 -DIHYDROBENZOFURANYL)-9H-PYRROLO-(3,4-B)QUINOLIN-9-ONE; MALE ERECTILE DYSFUNCTION; SEXUAL DISORDERS | SUI ZHIHUA (US) | 2004-11-16 | — | — | US | disclosed |