Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6773205 | 0.92 | PDE5A (0.58) | PDE5APDE6C | |
| SCHEMBL6777354 | 0.90 | PDE5A (0.58) | PDE5APDE6C | |
| SCHEMBL6777646 | 0.89 | PDE5A (0.58) | PDE5APDE6C | |
| SCHEMBL6778131 | 0.89 | PDE5A (0.58) | PDE5APDE6C | |
| SCHEMBL6782584 | 0.87 | PDE5A (0.55) | PDE5APDE6C | |
| SCHEMBL6782567 | 0.87 | PDE5A (0.55) | PDE5APDE6C | |
| SCHEMBL6776747 | 0.86 | PDE5A (0.56) | PDE5APDE6C | |
| SCHEMBL6778726 | 0.85 | PDE5A (0.52) | PDE5APDE6C | |
| SCHEMBL6777025 | 0.83 | PDE5A (0.51) | PDE5APDE6C | |
| SCHEMBL6772442 | 0.83 | PDE5A (0.50) | PDE5APDE6C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6756373-B1 | SUCH AS 5-(2-BUTOXY-5-IODO-3-PYRIDINYL)-3-ETHYL-2-(2-METHOXY-ETHYL)-2,6-DIHYDRO-7H -PYRAZOLO(4,3-D)PYRIMIDIN-7-ONE; CYCLIC GUANOSINE 3',5'-MONOPHOSPHATE PHOSPHODIESTERASE INHIBITORS; ERECTILE DYSFUNCTION | PFIZER INC. | 2004-06-29 | — | — | US | claimed |
| US-6756373-B1 | SUCH AS 5-(2-BUTOXY-5-IODO-3-PYRIDINYL)-3-ETHYL-2-(2-METHOXY-ETHYL)-2,6-DIHYDRO-7H -PYRAZOLO(4,3-D)PYRIMIDIN-7-ONE; CYCLIC GUANOSINE 3',5'-MONOPHOSPHATE PHOSPHODIESTERASE INHIBITORS; ERECTILE DYSFUNCTION | PFIZER INC. | 2004-06-29 | — | — | US | disclosed |