⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL159380 | 0.74 | — | — | |
| SCHEMBL6013871 | 0.70 | — | — | |
| SCHEMBL28277024 | 0.69 | — | — | |
| SCHEMBL2009490 | 0.67 | — | — | |
| SCHEMBL10621131 | 0.67 | — | — | |
| SCHEMBL12113169 | 0.67 | — | — | |
| SCHEMBL15626471 | 0.67 | — | — | |
| SCHEMBL7621913 | 0.65 | — | — | |
| SCHEMBL18722155 | 0.65 | EPHX1 (0.31) | — | |
| SCHEMBL11309703 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1992349-B1 | CGRP antagonists, their preparation and use as a medicament | BOEHRINGER INGELHEIM INT (DE) | 2013-07-31 | — | — | EP | claimed |
| CN-116710423-A | Method for producing organic compound | 奇华顿股份有限公司 | 2023-09-05 | — | — | CN | disclosed |
| US-20210395189-A1 | SUBSTITUTED TETRACYCLINE COMPOUNDS | PARATEK PHARMACEUTICALS, INC. | 2021-12-23 | — | — | US | disclosed |
| EP-3812372-A2 | 7-HETEROCYCLYL SUBSTITUTED SANCYCLINE DERIVATIVES FOR TREATING BACTERIAL, VIRAL AND PARASITIC INFECTIONS (E.G. MALARIA) OR INFLAMMATORY DISEASES | Paratek Pharmaceuticals, Inc. (US) | 2021-04-28 | — | — | EP | disclosed |
| EP-3045449-A1 | TETRACYCLINE DERIVATIVES FOR THE TREATMENT OF BACTERIAL, VIRAL AND PARASITIC INFECTIONS | Paratek Pharmaceuticals, Inc. (US) | 2016-07-20 | — | — | EP | disclosed |
| US-20160046561-A1 | SUBSTITUTED TETRACYCLINE COMPOUNDS | PARATEK PHARMACEUTICALS, INC. | 2016-02-18 | — | — | US | disclosed |
| US-9012433-B2 | Substituted tetracycline compounds | PARATEK PHARMACEUTICALS, INC. (US) | 2015-04-21 | — | — | US | disclosed |
| US-8653255-B2 | Sialic acid derivatives for protein derivatisation and conjugation | LIPOXEN TECHNOLOGIES LIMITED (GB) | 2014-02-18 | — | — | US | disclosed |
| EP-2684874-A1 | Fused bicyclic derivatives of 2,4-diaminopyrimidine as alk and C-met inhibitors | Cephalon, Inc. (US) | 2014-01-15 | — | — | EP | disclosed |
| US-8569239-B2 | Glutathione based delivery system | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2013-10-29 | — | — | US | disclosed |
| US-5104982-A | ROUTE TO GLYCALS IN THE ALLAL AND GULAL SERIES | YALE UNIVERSITY (US) | 1992-04-14 | — | — | US | disclosed |
| EP-0448412-A2 | A route to glycals in the allal and gulal series | YALE UNIVERSITY (US) | 1991-09-25 | — | — | EP | disclosed |
| WO-1991002739-A1 | SYNTHESIS OF GLYCOSIDES HAVING PREDETERMINED STEREOCHEMISTRY | YALE UNIVERSITY (US) | 1991-03-07 | — | — | WO | disclosed |
| US-4803263-A | Process for the preparation of alkylated glycosyl fluorides free from hydroxyl groups | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-02-07 | — | — | US | disclosed |
| US-4281116-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1981-07-28 | — | — | US | disclosed |
| US-4260745-A | 3-Halo cephalosporins | ELI LILLY AND COMPANY (US) | 1981-04-07 | — | — | US | disclosed |
| US-4252950-A | ANTIBIOTICS, BACTERICIDES, FUNGICIDES | ELI LILLY AND COMPANY (US) | 1981-02-24 | — | — | US | disclosed |
| US-4208515-A | 3-Halo cephalosporins | ELI LILLY AND COMPANY (US) | 1980-06-17 | — | — | US | disclosed |
| US-4065618-A | Process for 3-H-3-cephem esters | ELI LILLY AND COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-4064343-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1977-12-20 | — | — | US | disclosed |