Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6788555 | 1.00 | PARP1 (0.51) | PARP1PARP2 | |
| SCHEMBL6787793 | 1.00 | PARP1 (0.51) | PARP1PARP2 | |
| SCHEMBL6787963 | 0.90 | PARP1 (0.48) | PARP1PARP2 | |
| SCHEMBL6787134 | 0.88 | PARP1 (0.49) | PARP1PARP2 | |
| SCHEMBL6785917 | 0.88 | PARP1 (0.49) | PARP1PARP2 | |
| SCHEMBL6781757 | 0.88 | PARP1 (0.49) | PARP1PARP2 | |
| SCHEMBL6782909 | 0.87 | PARP1 (0.43) | PARP1PARP2 | |
| SCHEMBL5072053 | 0.86 | PARP1 (0.54) | PARP1PARP2 | |
| SCHEMBL6782750 | 0.85 | PARP1 (0.52) | PARP1PARP2 | |
| SCHEMBL6778530 | 0.85 | PARP1 (0.52) | PARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6737421-B1 | 4-CARBOXYAMIDO SUBSTITUTED; NEURODEGENERATIVE DISEASES; NEURONAL DAMAGE | ABBOTT GMBH & CO. KG (DE) | 2004-05-18 | — | — | US | disclosed |