⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL130332 | 0.72 | — | — | |
| SCHEMBL269948 | 0.69 | — | — | |
| SCHEMBL1435402 | 0.69 | — | — | |
| SCHEMBL11298691 | 0.69 | — | — | |
| SCHEMBL214876 | 0.67 | — | — | |
| SCHEMBL2558387 | 0.67 | — | — | |
| SCHEMBL27505449 | 0.67 | — | — | |
| SCHEMBL18632230 | 0.67 | — | — | |
| SCHEMBL18550127 | 0.67 | — | — | |
| SCHEMBL17400860 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10988482-B2 | IRAK4 inhibitor and use thereof | Beijing Hanmi Pharmaceutical Co., Ltd. (CN) | 2021-04-27 | — | — | US | disclosed |
| CN-107531725-B | IRAK4 inhibitor and application thereof | 北京韩美药品有限公司 | 2021-03-19 | — | — | CN | disclosed |
| EP-3336091-B1 | IRAK4 INHIBITOR AND USE THEREOF | BEIJING HANMI PHARMACEUTICAL CO LTD (CN) | 2020-12-02 | — | — | EP | disclosed |
| US-20200062775-A1 | IRAK4 INHIBITOR AND USE THEREOF | Beijing Hanmi Pharmaceutical Co., Ltd. (CN) | 2020-02-27 | — | — | US | disclosed |
| EP-3336091-A1 | IRAK4 INHIBITOR AND USE THEREOF | Beijing Hanmi Pharmaceutical Co., Ltd. (CN) | 2018-06-20 | — | — | EP | disclosed |
| CN-107531725-A | Irak4 inhibitor and application thereof | 北京韩美药品有限公司 | 2018-01-02 | — | — | CN | disclosed |
| CN-105609649-A | Organic electroluminescent device | SAMSUNG DISPLAY CO LTD | 2016-05-25 | — | — | CN | disclosed |
| US-6809101-B2 | RNA POLYMERASES INHIBITORS; SUCH AS 5-(1-HYDROXY-1-(5-METHYL-OXAZOL-2-YL))METHYLENE-2-THIOXOTHIAZOLIDIN-4-ONE | SHIONOGI & CO., LTD. (JP) | 2004-10-26 | — | — | US | disclosed |
| US-20030203948-A1 | Compounds having anti-hepatitics c virus effect | Z-KAT, INC. | 2003-10-30 | — | — | US | disclosed |
| CN-1304410-A | Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them | ASTRA ZENECA LTD (SE) | 2001-07-18 | — | — | CN | disclosed |