⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1193863 | 0.82 | — | — | |
| SCHEMBL7668632 | 0.78 | — | — | |
| SCHEMBL29152439 | 0.75 | — | — | |
| SCHEMBL4009786 | 0.75 | — | — | |
| SCHEMBL26340588 | 0.75 | — | — | |
| SCHEMBL11303032 | 0.75 | — | — | |
| Trichloroethane SCHEMBL1366178 | 0.73 | — | — | |
| SCHEMBL28679463 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL11197451 | 0.72 | — | — | |
| SCHEMBL10615083 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114085163-B | Method for synthesizing 2, 3-tetrafluoro-2- (trifluoromethyl) propionitrile by gas phase catalytic fluorination | 化学与精细化工广东省实验室 | 2023-10-27 | — | — | CN | claimed |
| CN-114085163-A | Method for synthesizing 2,3,3, 3-tetrafluoro-2- (trifluoromethyl) propionitrile by gas-phase catalytic fluorination | 化学与精细化工广东省实验室 | 2022-02-25 | — | — | CN | claimed |
| CN-114085163-B | Method for synthesizing 2, 3-tetrafluoro-2- (trifluoromethyl) propionitrile by gas phase catalytic fluorination | 化学与精细化工广东省实验室 | 2023-10-27 | — | — | CN | disclosed |
| US-11746178-B2 | Polymer production method and radical polymerization initiating group-containing compound | DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) | 2023-09-05 | — | — | US | disclosed |
| EP-3737684-B1 | 2,4,6,7-TETRAHYDRO-PYRAZOLO[4,3-D]PYRIMIDIN-5-ONE DERIVATIVES AND RELATED COMPOUNDS AS C5A RECEPTOR MODULATORS FOR TREATING VASCULITIS AND INFLAMMATORY DISEASES | IDORSIA PHARMACEUTICALS LTD (CH) | 2022-11-16 | — | — | EP | disclosed |
| CN-114085163-A | Method for synthesizing 2,3,3, 3-tetrafluoro-2- (trifluoromethyl) propionitrile by gas-phase catalytic fluorination | 化学与精细化工广东省实验室 | 2022-02-25 | — | — | CN | disclosed |
| US-20190135818-A1 | 5-MEMBERED HETEROCYCLE FUSED WITH [3,4-D] PYRIDAZINONE, AND MANUFACTURING METHOD, PHARMACEUTICAL COMPOSITION, AND APPLICATION THEREOF | SHANGHAI INST MATERIA MEDICA CAS (CN) | 2019-05-09 | — | — | US | disclosed |
| EP-3470415-A1 | 5-MEMBERED HETEROCYCLE FUSED WITH [3,4-D]PYRIDAZINONE, AND MANUFACTURING METHOD, PHARMACEUTICAL COMPOSITION, AND APPLICATION THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2019-04-17 | — | — | EP | disclosed |
| CN-105801347-A | Removing method for nitrile organic matter in tetrachloroethylene and carbon tetrachloride | 巨化集团技术中心 | 2016-07-27 | — | — | CN | disclosed |
| EP-1619211-B1 | PROCESS FOR PRODUCTION OF LIVING-RADICAL POLYMERS AND POLYMERS | OTSUKA CHEMICAL CO LTD (JP) | 2012-10-17 | — | — | EP | disclosed |
| WO-2012125667-A1 | TrkA KINASE INHIBITORS, COMPOSITIONS AND METHODS THEREOF | MERCK SHARP & DOHME CORP. (US) | 2012-09-20 | — | — | WO | disclosed |
| US-20050245714-A1 | Organic tellurium compound, process for producing the same, living radical polymerization initiator, process for producing polymer with the same, and polymer | OTSUKA CHEMICAL CO., LTD. (JP) | 2005-11-03 | — | — | US | disclosed |
| CN-1675253-A | Method for producing living radical polymer and polymer | OTSUKA CHEMICAL CO LTD (JP) | 2005-09-28 | — | — | CN | disclosed |
| CN-1649838-A | Organic tellurium compound, method for producing same, living radical polymerization initiator, method for producing polymer using same, and polymer | OTSUKA KAGAKU KK (JP) | 2005-08-03 | — | — | CN | disclosed |
| EP-1541550-A1 | ORGANIC TELLURIUM COMPOUND, PROCESS FOR PRODUCING THE SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER WITH THE SAME, AND POLYMER | Otsuka Chemical Co., Ltd. (JP) | 2005-06-15 | — | — | EP | disclosed |
| EP-1541592-A1 | PROCESS FOR PRODUCTION OF LIVING RADICAL POLYMERS AND POLYMERS | OTSUKA CHEMICAL COMPANY, LIMITED (JP) | 2005-06-15 | — | — | EP | disclosed |
| US-6353127-B1 | α-chloronitriles production method | BASF AKTIENGESELLSCHAFT (DE) | 2002-03-05 | — | — | US | disclosed |
| US-4375555-A | BY REACTING A CYANOHYDRIN WITH THIONYL CHLORIDE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 1983-03-01 | — | — | US | disclosed |
| US-4371705-A | FROM ALDEHYDES OR KETONES AND METAL CYANIDES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 1983-02-01 | — | — | US | disclosed |
| US-4370493-A | BY REACTING A CYANOHYDRIN WITH THIONYL CHLORIDE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF ENERGY (US) | 1983-01-25 | — | — | US | disclosed |