Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | F10 | P00742 | 16/20 | 0.49 |
| ▸ | F2 | P00734 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL6725746 | 0.85 | F10 (0.52) | F10 | |
| Iodide SCHEMBL6731640 | 0.84 | F10 (0.43) | ALDH1A1F10F2 | |
| Iodide SCHEMBL6735559 | 0.82 | F10 (0.46) | ALDH1A1F10F2 | |
| Iodide SCHEMBL6731308 | 0.81 | F10 (0.41) | ALDH1A1F10F2 | |
| Iodide SCHEMBL6731432 | 0.81 | F10 (0.49) | F10F2 | |
| Iodide SCHEMBL6731165 | 0.80 | F10 (0.45) | ALDH1A1F10F2 | |
| Iodide SCHEMBL6736671 | 0.80 | F10 (0.40) | ALDH1A1F10F2 | |
| Iodide SCHEMBL6728938 | 0.79 | F10 (0.43) | ALDH1A1F10F2 | |
| Iodide SCHEMBL6786318 | 0.78 | F10 (0.43) | F10F2 | |
| Iodide SCHEMBL6781771 | 0.78 | F10 (0.49) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6747023-B1 | INHIBITORS FOR ACTIVATED COAGULATION FACTOR X, COAGULATION SUPPRESSORS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-06-08 | — | — | US | disclosed |
| EP-1104754-A1 | NOVEL SULFONYL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-06-06 | — | — | EP | disclosed |