SCHEMBL6784537

SCHEMBL6784537

CCC(F)C(F)(F)Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15263930 0.77
SCHEMBL45302 0.73
SCHEMBL10363024 0.71
SCHEMBL6408429 0.71
SCHEMBL23825200 0.69
SCHEMBL5717173 0.69
SCHEMBL7659549 0.69
SCHEMBL3674576 0.69
SCHEMBL578680 0.69
SCHEMBL1020281 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1128535-A Process for preparing fluoroalkenylthio heterocyclic derivatives ZENECA LTD (GB) 1996-08-07 CN claimed
EP-4682141-A1 TRICYCLIC COMPOUND ONO Pharmaceutical Co., Ltd. (JP) 2026-01-21 EP disclosed
CN-108084143-B Method for continuously preparing 4-trifluoromethyl ethylene carbonate 西安近代化学研究所 2021-02-26 CN disclosed
US-9187446-B2 Antibacterial agents: sidechainfluorinated myxopyronin derivatives RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2015-11-17 US disclosed
US-20150051275-A1 ANTIBACTERIAL AGENTS: SIDECHAINFLUORINATED MYXOPYRONIN DERIVATIVES HOWARD HUGHES MEDICAL INSTITUTE 2015-02-19 US disclosed
WO-2013142812-A1 ANTIBACTERIAL AGENTS: SIDECHAIN-FLUORINATED MYXOPYRONIN DERIVATIVES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2013-09-26 WO disclosed
CN-1809543-A Nematicidal thiazoline-containing fluorobutenes BAYER CROPSCIENCE AG (DE) 2006-07-26 CN disclosed
US-6720342-B2 AZABICYCLIC COMPOUNDS USED IN TREATING A DISEASE IN THE CENTRAL NERVOUS SYSTEM CAUSED BY MALFUNCTIONING OF THE MUSCARINIC CHOLINERGIC SYSTEM. NOVO NORDISK A/S (DK) 2004-04-13 US disclosed
US-20020115697-A1 Heterocyclic compounds and their preparation and use JEPPESEN LONE (DK) 2002-08-22 US disclosed
EP-0900217-A4 HETEROCYCLIC COMPOUNDS LILLY CO ELI (US) 2001-05-23 EP disclosed
CN-1143958-A (4,4-difluorobut-3-enylthio-)-substituted heterocyclic or carbocyclic ring compounds ZENECA LTD (GB) 1997-02-26 CN disclosed
CN-1128535-A Process for preparing fluoroalkenylthio heterocyclic derivatives ZENECA LTD (GB) 1996-08-07 CN disclosed
WO-1995028413-A1 17β-SUBSTITUTED 3-CARBOXY STEROIDS THAT INHIBIT 5-α-REDUCTASE SMITHKLINE BEECHAM CORPORATION (US) 1995-10-26 WO disclosed
CN-1098718-A Heterogeneous ring compound ZENECA LTD (GB) 1995-02-15 CN disclosed
CN-1094400-A Heterogeneous ring compound ZENECA LTD (GB) 1994-11-02 CN disclosed
WO-1993003113-A1 LIQUID-CRYSTAL COMPOUNDS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1993-02-18 WO disclosed
EP-0525140-A1 LIQUID-CRYSTAL COMPOUNDS MERCK PATENT GmbH (DE) 1993-02-03 EP disclosed
WO-1992013928-A1 LIQUID-CRYSTAL COMPOUNDS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1992-08-20 WO disclosed
US-4552883-A CNS DEPRESSANTS, ANXIOLYTICS ICI AMERICAS INC. (US) 1985-11-12 US disclosed
EP-0096995-A2 Pyrazolopyridine compounds ICI AMERICAS INC. (US) 1983-12-28 EP disclosed