SCHEMBL6784677

SCHEMBL6784677

CNC(=O)C1CN(S(=O)(=O)c2cc3cc(Cl)ccc3[nH]2)CCN1C(=O)c1nc2c(s1)CNCC2

nearest known ligand 0.63

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.63
F2 P00734 8/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6729419 0.99 F10 (0.62) F10F2
Hydrochloric Acid SCHEMBL6725058 0.88 F10 (0.75) F10F2
SCHEMBL6732084 0.88 F10 (0.56) F10F2
SCHEMBL6729541 0.88 F10 (0.56) F10F2
SCHEMBL4464048 0.87 F10 (0.65) F10F2
Hydrochloric Acid SCHEMBL6729553 0.87 F10 (0.55) F10F2
SCHEMBL6733880 0.87 F10 (0.55) F10F2
Hydrochloric Acid SCHEMBL6737384 0.84 F10 (0.57) F10F2
Hydrochloric Acid SCHEMBL6733784 0.84 F10 (0.60) F10F2
SCHEMBL6736652 0.84 F10 (0.52) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6747023-B1 INHIBITORS FOR ACTIVATED COAGULATION FACTOR X, COAGULATION SUPPRESSORS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-06-08 US disclosed
EP-1104754-A1 NOVEL SULFONYL DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2001-06-06 EP disclosed