Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 18/20 | 0.72 |
| ▸ | NQO2 | P16083 | 2/20 | 0.64 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.64 |
| ▸ | F10 | P00742 | 1/20 | 0.64 |
| ▸ | PLG | P00747 | 1/20 | 0.64 |
| ▸ | PLAT | P00750 | 1/20 | 0.64 |
| ▸ | PROC | P04070 | 1/20 | 0.64 |
| ▸ | HPN | P05981 | 1/20 | 0.64 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.64 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.64 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.64 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.64 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.64 |
| ▸ | KLK1 | P06870 | 1/20 | 0.58 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6779711 | 0.91 | NQO2 (0.65) | F2NQO2SLC22A2F10PLG | |
| SCHEMBL6779434 | 0.90 | F2 (0.61) | F2NQO2SLC22A2F10PLG | |
| SCHEMBL6637006 | 0.85 | F2 (0.75) | F2NQO2SLC22A2F10PLG | |
| SCHEMBL505887 | 0.84 | F2 (1.00) | F2NQO2SLC22A2F10PLG | |
| SCHEMBL505899 | 0.82 | F2 (1.00) | F2NQO2SLC22A2F10PLG | |
| Hydrochloric Acid SCHEMBL6778118 | 0.81 | F2 (0.98) | F2NQO2SLC22A2F10PLG | |
| Hydrochloric Acid SCHEMBL6778817 | 0.81 | NQO2 (0.58) | F2NQO2SLC22A2F10PLG | |
| SCHEMBL506727 | 0.81 | F2 (0.89) | F2NQO2SLC22A2F10PLG | |
| Hydrochloric Acid SCHEMBL6784210 | 0.80 | F2 (0.88) | F2NQO2SLC22A2F10PLG | |
| SCHEMBL6639400 | 0.80 | F2 (0.63) | F2NQO2SLC22A2F10PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6710055-B2 | INDOLE AND BENZIMIDAZOLE ANTITHROMBOTIC COMPOUNDS, SUCH AS 1-METHYL-2-(N-AMIDINOPHENYL)-AMINOMETHYL)-5-(N-(HYDROXYCARBO QUINOLINE-8-SULFONYLAMINO)-INDOLE | BOEHRINGER INGELHEIM PHARMA GMBH & CO., KG (DE) | 2004-03-23 | — | — | US | disclosed |
| EP-0966454-B1 | DISUBSTITUTED BICYCLIC HETEROCYCLES, THEIR PRODUCTION AND USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-05-07 | — | — | EP | disclosed |
| US-6469039-B1 | BENZIMIDAZOLES; THROMBIN- INHIBITING ACTIVITY AND THE EFFECT OF EXTENDING THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-10-22 | — | — | US | disclosed |
| US-6414008-B1 | CYNAO- OR AMIDINE-SUBSTITUTED BENZIMIDAZOLES, BENOTHIAZOLES, OR BENZOXAZOLES; 2-(N-(4-AMIDINOPHENYL)AMINOMETHYL)BENZOTHIAZOLES; 2-((4-CYANOPHENYL)OXYMETHYL)IMIDAZOL(4,5-B)PYRIDINES; ANTITHROMBOTICS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-07-02 | — | — | US | disclosed |
| US-6087380-A | ANTITHROMBOTIC BENZIMIDAZOLES; ANTICOAGULANTS; 2-(N-(4-AMIDINOPHENYL)-AMINOMETHYL)-BENZIMIDAZOL-5-YL-CARBOXYLIC ACIDS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-07-11 | — | — | US | disclosed |