Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | ACR | P10323 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20202771 | 0.89 | MAPT (0.59) | PPARACYP1A1CYP1B1MAPTKDM4E | |
| SCHEMBL2671840 | 0.88 | PPARA (0.46) | PPARACYP1A1CYP1B1MAPTKDM4E | |
| SCHEMBL2671839 | 0.88 | PPARA (0.46) | PPARACYP1A1CYP1B1MAPTKDM4E | |
| SCHEMBL864924 | 0.88 | PPARA (0.46) | PPARACYP1A1CYP1B1MAPTKDM4E | |
| SCHEMBL864925 | 0.88 | PPARA (0.46) | PPARACYP1A1CYP1B1MAPTKDM4E | |
| SCHEMBL3630763 | 0.87 | MAPT (0.45) | PPARACYP1A1CYP1B1MAPTKDM4E | |
| SCHEMBL19193806 | 0.86 | MAPT (0.47) | PPARACYP1A1CYP1B1MAPTKDM4E | |
| SCHEMBL19193699 | 0.85 | CYP1A1 (0.51) | CYP1A1CYP1B1MAPTKDM4EABCG2 | |
| SCHEMBL22171289 | 0.85 | ABCG2 (0.49) | CYP1A1CYP1B1MAPTKDM4EABCG2 | |
| SCHEMBL22639614 | 0.84 | MAPT (0.49) | PPARAMAPTPRSS1ACRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110065859-A1 | THERMALLY STABLE ALIGNMENT MATERIALS | ROLIC AG (CH) | 2011-03-17 | — | — | US | disclosed |
| US-20110065859-A1 | THERMALLY STABLE ALIGNMENT MATERIALS | ROLIC AG (CH) | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065859-A1 | THERMALLY STABLE ALIGNMENT MATERIALS | PARG, PARN, PUF60 | PPARA 3612/4885CYP1A1 4764/4885CYP1B1 4620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.