Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSF1 | Q00613 | 1/20 | 0.70 |
| ▸ | BCL6 | P41182 | 1/20 | 0.44 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 4/20 | 0.39 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9985027 | 0.89 | HSF1 (0.68) | HSF1BRD4POLBMAPTMAOB | |
| SCHEMBL9985913 | 0.84 | HSF1 (0.61) | HSF1BRD4POLBMAPTMAOB | |
| SCHEMBL9986208 | 0.83 | HSF1 (0.71) | HSF1BRD4POLBMAPTMAOB | |
| SCHEMBL6909979 | 0.83 | HSF1 (0.74) | HSF1BRD4POLBMAPTMAOB | |
| SCHEMBL9985474 | 0.83 | HSF1 (0.71) | HSF1BRD4POLBMAPTMAOB | |
| SCHEMBL6783318 | 0.82 | HSF1 (1.00) | HSF1BRD4POLBMAPTMAOB | |
| SCHEMBL29380539 | 0.82 | HSF1 (1.00) | HSF1BRD4POLBMAPTMAOB | |
| SCHEMBL29695497 | 0.82 | HSF1 (1.00) | HSF1BRD4POLBMAPTMAOB | |
| SCHEMBL27595861 | 0.82 | HSF1 (0.69) | HSF1BRD4POLBMAPTMAOB | |
| SCHEMBL9985353 | 0.82 | HSF1 (0.69) | HSF1BRD4POLBMAPTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6743795-B1 | INHIBITORS FOR HEPATITIS B AND ACQUIRED IMMUNE DEFICIENCY SYNDROME (AIDS) BECAUSE THEY INTERFERE WITH REMOVAL OF RNA STRAND FROM RNA-DNA HYBRID FORMED DURING THE REVERSE TRANSCRIPTION OF VIRAL RNA TO DNA | DONG WHA PHARM. IND. CO. LTD. (KR) | 2004-06-01 | — | — | US | disclosed |