SCHEMBL6786155

SCHEMBL6786155

CC(C)(C)OC(=O)CC(N)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.47
HDAC3 O15379 1/20 0.46
HDAC1 Q13547 1/20 0.46
HDAC2 Q92769 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
CA2 P00918 2/20 0.32
CA1 P00915 1/20 0.32
CA7 P43166 1/20 0.32
DGAT1 O75907 1/20 0.32
NOS1 P29475 2/20 0.32
NOS3 P29474 1/20 0.32
NOS2 P35228 1/20 0.32
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32
KMT2A Q03164 1/20 0.32
SLC7A5 Q01650 1/20 0.31
MLYCD O95822 5/20 0.31
CA12 O43570 1/20 0.31
CA14 Q9ULX7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20967746 1.00 CYP2D6 (0.47) CYP2D6HDAC3HDAC1HDAC2HDAC8
SCHEMBL2331892 0.84 CYP2D6 (0.44) CYP2D6HDAC3HDAC1HDAC2HDAC8
SCHEMBL31301962 0.84 CYP2D6 (0.44) CYP2D6HDAC3HDAC1HDAC2HDAC8
SCHEMBL21320780 0.83 CYP2D6 (0.45) CYP2D6HDAC3HDAC1HDAC2HDAC8
SCHEMBL2153662 0.83 CYP2D6 (0.53) CYP2D6HDAC3HDAC1HDAC2HDAC8
SCHEMBL318355 0.82 CYP2D6 (0.47) CYP2D6HDAC3HDAC1HDAC2HDAC8
SCHEMBL29086468 0.82 CYP2D6 (0.43) CYP2D6HDAC3HDAC1HDAC2HDAC8
SCHEMBL3624697 0.82 CYP2D6 (0.47) CYP2D6HDAC3HDAC1HDAC2HDAC8
SCHEMBL1964905 0.82 CYP2D6 (0.47) CYP2D6HDAC3HDAC1HDAC2HDAC8
SCHEMBL6154559 0.81 CYP2D6 (0.50) CYP2D6HDAC3HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3911795-A1 METHOD OF STRENGTHENING NON-KERATINOUS FIBERS, AND USES THEREOF ISP Investments LLC (US) 2021-11-24 EP claimed
WO-2020150384-A1 METHOD OF STRENGTHENING NON-KERATINOUS FIBERS, AND USES THEREOF ISP INVESTMENTS LLC (US) 2020-07-23 WO claimed
CN-107236073-A A kind of preparation method of antibacterial super branched polyacrylate optical liquid rubber 东莞市联洲知识产权运营管理有限公司 2017-10-10 CN claimed
EP-3911795-A1 METHOD OF STRENGTHENING NON-KERATINOUS FIBERS, AND USES THEREOF ISP Investments LLC (US) 2021-11-24 EP disclosed
WO-2020150384-A1 METHOD OF STRENGTHENING NON-KERATINOUS FIBERS, AND USES THEREOF ISP INVESTMENTS LLC (US) 2020-07-23 WO disclosed
CN-110483758-A A kind of preparation method of monoamine base polyoxyethylene ether ZHEJIANG HUANGMA TECH CO LTD 2019-11-22 CN disclosed
CN-108395413-B A kind of preparation method of morpholine -3- carboxylic acid 上海馨远医药科技有限公司 2019-05-28 CN disclosed
CN-109762170-A A kind of polyphosphate polymer and preparation method thereof, modified porous silicon nanoparticle and its preparation method and application 华中科技大学 2019-05-17 CN disclosed
CN-107236073-A A kind of preparation method of antibacterial super branched polyacrylate optical liquid rubber 东莞市联洲知识产权运营管理有限公司 2017-10-10 CN disclosed
EP-2670732-A2 ISOCYANATE MANUFACTURE Warsaw Orthopedic, Inc. (US) 2013-12-11 EP disclosed
US-8552217-B2 Isocyanate manufacture WARSAW ORTHOPEDIC, INC. (US) 2013-10-08 US disclosed
WO-2000047693-A9 LUMINESCENT METAL-LIGAND COMPLEXES LJL BIOSYSTEMS INC (US) 2002-04-11 WO disclosed
WO-2002016327-A1 BENZIMIDAZOLES AND ANALOGUES AND THEIR USE AS NEUTROPHIL INHIBITORS THE PROCTER & GAMBLE COMPANY (US) 2002-02-28 WO disclosed
EP-1181269-A1 CELL PROLIFERATION INHIBITORS ABBOTT LABORATORIES (US) 2002-02-27 EP disclosed
US-20010021514-A1 Luminescent metal-ligand complexes LJL BIOSYSTEMS, INC. 2001-09-13 US disclosed
WO-2000073264-A1 CELL PROLIFERATION INHIBITORS ABBOTT LABORATORIES (US) 2000-12-07 WO disclosed
CN-1058969-C Novel substd. guanidine derivs., process for prodn. thereof, and pharmaceutical uses thereof SUMITOMO PHARMA (JP) 2000-11-29 CN disclosed
WO-2000047693-A1 LUMINESCENT METAL-LIGAND COMPLEXES LJL BIOSYSTEMS, INC. (US) 2000-08-17 WO disclosed
CN-1161334-A Novel substd. guanidine derivs., process for prodn. thereof, and pharmaceutical uses thereof SUMITOMO PHARMA (JP) 1997-10-08 CN disclosed
EP-0556216-B1 PHOSPHORIC ACID ESTERS AND THEIR USE IN THE PREPARATION OF BIOCOMPATIBLE SURFACES BIOCOMPATIBLES LTD (GB) 1997-06-04 EP disclosed