Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 10/20 | 0.44 |
| ▸ | LSS | P48449 | 2/20 | 0.43 |
| ▸ | KLK1 | P06870 | 1/20 | 0.42 |
| ▸ | MAP2 | P11137 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6729341 | 0.95 | F10 (0.46) | F10KLK1MAP2ALDH1A1L3MBTL1 | |
| SCHEMBL6730822 | 0.94 | LSS (0.48) | F10LSSKLK1MAP2ALDH1A1 | |
| SCHEMBL6729605 | 0.86 | F10 (0.44) | F10KLK1MAP2LMNA | |
| SCHEMBL6781215 | 0.86 | F10 (0.37) | F10KLK1ALDH1A1L3MBTL1LMNA | |
| SCHEMBL6733829 | 0.86 | F10 (0.49) | F10KLK1MAP2 | |
| SCHEMBL6733956 | 0.84 | F10 (0.47) | F10KLK1MAP2ALDH1A1L3MBTL1 | |
| SCHEMBL6726115 | 0.84 | F10 (0.50) | F10LSSKLK1MAP2ALDH1A1 | |
| SCHEMBL6730891 | 0.82 | F10 (0.51) | F10LSSKLK1MAP2ALDH1A1 | |
| SCHEMBL6729442 | 0.81 | F10 (0.47) | F10KLK1MAP2LMNA | |
| SCHEMBL6735051 | 0.80 | F10 (0.46) | F10KLK1MAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6747023-B1 | INHIBITORS FOR ACTIVATED COAGULATION FACTOR X, COAGULATION SUPPRESSORS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-06-08 | — | — | US | disclosed |