SCHEMBL6786305

SCHEMBL6786305

CC1SC2=C(CCN(C(=O)N3CCN(S(=O)(=O)c4cc5ccc(Cl)cc5s4)CC3)N2)N1C

nearest known ligand 0.49

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6738149 0.88 F10 (0.36) F10
SCHEMBL6736630 0.85 F10 (0.44) F10
SCHEMBL6729460 0.85 F10 (0.48) F10
SCHEMBL6731266 0.83 F10 (0.57) F10
SCHEMBL6728081 0.83 F10 (0.44) F10
SCHEMBL6729828 0.83 F10 (0.58) F10
SCHEMBL6733592 0.82 F10 (0.49) F10
SCHEMBL6729054 0.80 F10 (0.50) F10
SCHEMBL6729643 0.76 F10 (0.50) F10
SCHEMBL6731543 0.74 F10 (0.35) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6747023-B1 INHIBITORS FOR ACTIVATED COAGULATION FACTOR X, COAGULATION SUPPRESSORS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-06-08 US disclosed
EP-1104754-A1 NOVEL SULFONYL DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2001-06-06 EP disclosed