Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 20/20 | 1.00 |
| ▸ | PDGFRB | P09619 | 18/20 | 1.00 |
| ▸ | KDR | P35968 | 18/20 | 1.00 |
| ▸ | FLT1 | P17948 | 5/20 | 0.70 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3382340 | 0.93 | FGFR1 (0.87) | FGFR1PDGFRBKDRFLT1CHEK1 | |
| SCHEMBL3381669 | 0.93 | FGFR1 (0.87) | FGFR1PDGFRBKDRFLT1CHEK1 | |
| SCHEMBL3381663 | 0.93 | FGFR1 (0.87) | FGFR1PDGFRBKDRFLT1CHEK1 | |
| SCHEMBL14795918 | 0.91 | FGFR1 (0.83) | FGFR1PDGFRBKDRFLT1CHEK1 | |
| SCHEMBL3381674 | 0.91 | FGFR1 (0.83) | FGFR1PDGFRBKDRFLT1CHEK1 | |
| SCHEMBL3382598 | 0.87 | FGFR1 (0.77) | FGFR1PDGFRBKDRFLT1CHEK1 | |
| SCHEMBL3741850 | 0.87 | FGFR1 (0.77) | FGFR1PDGFRBKDRFLT1CHEK1 | |
| SCHEMBL3379965 | 0.85 | FGFR1 (0.75) | FGFR1PDGFRBKDRFLT1CHEK1 | |
| SCHEMBL3381503 | 0.84 | FGFR1 (0.73) | FGFR1PDGFRBKDRFLT1CHEK1 | |
| SCHEMBL14795895 | 0.83 | FGFR1 (0.77) | FGFR1PDGFRBKDRFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800760-B2 | INHIBITORS OF VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR TYROSINE KINASE | CHIRON CORPORATION | 2004-10-05 | — | — | US | disclosed |