Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 5/20 | 0.96 |
| ▸ | DAO | P14920 | 5/20 | 0.96 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.96 |
| ▸ | IDH1 | O75874 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Kojic Acid SCHEMBL5011817 | 0.98 | TYR (1.00) | TYRDAOKDM4EIDH1 | |
| Kojic Acid SCHEMBL36895 | 0.98 | TYR (1.00) | TYRDAOKDM4EIDH1 | |
| Kojic Acid SCHEMBL28650749 | 0.96 | TYR (0.96) | TYRDAOKDM4EIDH1 | |
| Kojic Acid SCHEMBL28491069 | 0.96 | TYR (0.96) | TYRDAOKDM4EIDH1 | |
| Kojic Acid SCHEMBL30518398 | 0.96 | TYR (0.96) | TYRDAOKDM4EIDH1 | |
| Kojic Acid SCHEMBL29043760 | 0.96 | TYR (0.96) | TYRDAOKDM4EIDH1 | |
| Kojic Acid SCHEMBL9780977 | 0.96 | TYR (0.96) | TYRDAOKDM4EIDH1 | |
| Kojic Acid SCHEMBL28808848 | 0.96 | TYR (0.96) | TYRDAOKDM4EIDH1 | |
| Kojic Acid SCHEMBL12538255 | 0.96 | TYR (0.96) | TYRDAOKDM4EIDH1 | |
| Kojic Acid SCHEMBL28654757 | 0.96 | TYR (0.96) | TYRDAOKDM4EIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103228142-A | GABA agonists for the treatment of diseases associated with metabolic syndrome and GABA combinations for the treatment or prevention of type I diabetes | UNIV CALIFORNIA | 2013-07-31 | — | — | CN | claimed |
| CN-117693516-A | Crystalline forms of neuroactive steroid | 萨奇治疗股份有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-115768781-A | 3. Alpha, hydroxy, 17, beta, C (O) -N-aryl substituted neuroactive steroids and compositions thereof | 萨奇治疗股份有限公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-107050456-A | The gaba agonist for treating Metabolic Syndrome and the GABA combinations for treating or preventing type i diabetes | 加利福尼亚大学董事会 | 2017-08-18 | — | — | CN | disclosed |
| CN-103228142-A | GABA agonists for the treatment of diseases associated with metabolic syndrome and GABA combinations for the treatment or prevention of type I diabetes | UNIV CALIFORNIA | 2013-07-31 | — | — | CN | disclosed |
| US-20040197268-A1 | Method of imaging amyloid deposits using substituted rhodanine derivatives | AUGELLI-SZAFRAN CORINNE ELIZAB (US) | 2004-10-07 | — | — | US | disclosed |
| EP-1192144-A1 | RHODANINE DERIVATIVES AND THEIR USE IN INHIBITING AND IMAGING AMYLOIDS | WARNER-LAMBERT COMPANY (US) | 2002-04-03 | — | — | EP | disclosed |
| WO-2000076988-A1 | RHODANINE DERIVATIVES AND THEIR USE IN INHIBITING AND IMAGING AMYLOIDS | WARNER-LAMBERT COMPANY (US) | 2000-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040197268-A1 | Method of imaging amyloid deposits using substituted rhodanine derivatives | APP, PSEN1, PSEN2 | TYR 1394/4885DAO 1243/4885KDM4E 4641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.