SCHEMBL6787641

SCHEMBL6787641

CC1Cc2nc(C(=O)N3CCN(S(=O)(=O)c4cc5cc(Cl)ccc5[nH]4)CC3CCS(=O)(=O)N3CCOCC3)sc2CN1

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.48
F2 P00734 4/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6733672 0.94 F10 (0.49) F10F2
Hydrochloric Acid SCHEMBL6736380 0.94 F10 (0.46) F10F2
SCHEMBL6725883 0.91 F10 (0.39) F10F2
SCHEMBL6728331 0.91 F10 (0.54) F10F2
SCHEMBL6726504 0.90 F10 (0.47) F10F2
SCHEMBL6729641 0.90 F10 (0.48) F10F2
SCHEMBL6787320 0.89 F10 (0.61) F10F2
Hydrochloric Acid SCHEMBL6731342 0.89 F10 (0.60) F10F2
SCHEMBL6728729 0.88 F10 (0.47) F10F2
SCHEMBL6783813 0.88 F10 (0.47) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6747023-B1 INHIBITORS FOR ACTIVATED COAGULATION FACTOR X, COAGULATION SUPPRESSORS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-06-08 US disclosed
EP-1104754-A1 NOVEL SULFONYL DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2001-06-06 EP disclosed