Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985531 | 0.82 | HTR2C (0.32) | HTR2AHTR2CHTR2BRECQL | |
| SCHEMBL3625731 | 0.82 | CYP2C19 (0.35) | HTR2AHTR2CHTR2BRECQL | |
| SCHEMBL6607744 | 0.78 | HTR2A (0.31) | HTR2AHTR2CHTR2BRECQL | |
| SCHEMBL5390121 | 0.78 | CHRNA7 (0.33) | HTR2AHTR2CHTR2BRECQL | |
| SCHEMBL7197723 | 0.74 | — | — | |
| SCHEMBL9261393 | 0.74 | — | — | |
| SCHEMBL8582650 | 0.74 | — | — | |
| SCHEMBL17144244 | 0.74 | — | — | |
| SCHEMBL3583056 | 0.74 | GRM1 (0.35) | RECQL | |
| SCHEMBL7511837 | 0.73 | KDM1A (0.40) | HTR2AHTR2CHTR2BRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4544735-A | Preparation of poly(arylene sulfide) from halothiophenol and alkaline metal hydroxide | PHILLIPS PETROLEUM COMPANY (US) | 1985-10-01 | — | — | US | claimed |
| US-6765003-B1 | ANTICARCINOGENIC, ANTITUMOR, AND ANTIMETASTASIS AGENTS; RHEUMATOID ARTHRITIS, OSTEOARTHRITIS, OSTEOPOROSIS, MULTIPLE SCLEROSIS, STROKE, ARTERIOSCLEROSIS, | PHARMACIA ITALIA, SPA (IT) | 2004-07-20 | — | — | US | disclosed |
| EP-1200398-A1 | 3-ARYLSULFONYL-2-(SUBSTITUTED METHYL)PROPANOIC ACID DERIVATES AS MATRIX METALLOPROTEINASE INHIBITORS | Pharmacia Italia S.p.A. (IT) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001005756-A1 | 3-ARYLSULFONYL-2-(SUBSTITUTED METHYL)PROPANOIC ACID DERIVATES AS MATRIX METALLOPROTEINASE INHIBITORS | PHARMACIA & UPJOHN SPA (IT) | 2001-01-25 | — | — | WO | disclosed |
| US-5328980-A | Promoters with halothiophenol compounds and polar organic compounds | PHILLIPS PETROLEUM COMPANY (US) | 1994-07-12 | — | — | US | disclosed |
| EP-0604778-A2 | Method of preparing poly(arylene sulfide)polymers, polymers, and polymer blends | PHILLIPS PETROLEUM COMPANY (US) | 1994-07-06 | — | — | EP | disclosed |
| US-4544735-A | Preparation of poly(arylene sulfide) from halothiophenol and alkaline metal hydroxide | PHILLIPS PETROLEUM COMPANY (US) | 1985-10-01 | — | — | US | disclosed |