Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25072482 | 0.77 | — | — | |
| SCHEMBL8789178 | 0.74 | HCAR2 (0.30) | TYMPKMT2A | |
| SCHEMBL25307884 | 0.69 | DYRK1A (0.35) | TYMPKMT2A | |
| SCHEMBL29194141 | 0.67 | — | — | |
| SCHEMBL19668561 | 0.66 | AR (0.34) | AR | |
| SCHEMBL599352 | 0.64 | NPSR1 (0.57) | POLBALDH1A1AR | |
| SCHEMBL22164629 | 0.64 | TYMP (0.35) | TYMP | |
| SCHEMBL2361036 | 0.64 | TYMP (0.43) | TYMPKMT2AALDH1A1AR | |
| SCHEMBL9015978 | 0.64 | AR (0.33) | AR | |
| SCHEMBL24687302 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800758-B1 | REACTING 4-(3-HALOPROPYLAMINO)-5- CHLORO-3(2H)-PYRIDAZINONE WITH N-METHYL- HOMOVERATRYLAMINE IN PRESENCE OF ACID BINDING AGENT AND DIPOLAR APROTIC SOLVENT | EGIS GYOGYSZERGYAR RT. (HU) | 2004-10-05 | — | — | US | disclosed |
| EP-0275997-B1 | 3(2H)PYRIDAZINONE, PROCESS FOR ITS PREPARATION AND ANTAGONISTIC AGENT AGAINST SRS-A CONTAINING IT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-12-23 | — | — | EP | disclosed |
| US-5011839-A | Antagonists to slow reacting substance of anaphylaxis | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1991-04-30 | — | — | US | disclosed |
| US-4978665-A | ANTIALLERGENS | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1990-12-18 | — | — | US | disclosed |
| EP-0376079-A1 | 3(2H)pyridazinones, processes for their preparation and antagonistic agent against SRS-A | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1990-07-04 | — | — | EP | disclosed |
| EP-0275997-A1 | 3(2H)pyridazinone, process for its preparation and antagonistic agent against SRS-A containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1988-07-27 | — | — | EP | disclosed |