Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | ICMT | O60725 | 2/20 | 0.38 |
| ▸ | ALB | P02768 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27533268 | 1.00 | NPC1 (0.46) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL18560078 | 0.93 | NR1H2 (0.42) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL6792543 | 0.89 | TP53 (0.39) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL5715726 | 0.86 | NPC1 (0.44) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL5715943 | 0.86 | NPC1 (0.44) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL7038494 | 0.81 | NPC1 (0.45) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL6793642 | 0.79 | NR1H2 (0.43) | NPC1JAK2RAB9APAX8NR1H2 | |
| SCHEMBL5715840 | 0.78 | NPC1 (0.38) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL1258398 | 0.77 | TSHR (0.42) | KCNH2NR1H2NR1H3OPRM1DRD3 | |
| SCHEMBL27283717 | 0.76 | NPC1 (0.41) | NPC1JAK2RAB9APAX8KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6822057-B2 | OLEFIN POLYMERIZATION CATALYST SYSTEM IS A REACTION PRODUCT OF A METALLOCENES AND A COCATALYST CONTAINING FLUOROARYL SUBSTITUTED SECONDARY AMINE OR PHSOPHINE COMPOUND AND AN ANION CONTAINING GROUP 13 ELEMENT WHICH IS NONCOORDINATIG | EXXON MOBIL CHEMICAL PATENTS INC. | 2004-11-23 | — | — | US | disclosed |
| US-6489480-B2 | COORDINATION POLYMERIZATION CATALYST FOR ALPHA-OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. | 2002-12-03 | — | — | US | disclosed |
| US-20020115806-A1 | Olefin polymerization catalysts derived from Group-15 cationic compounds and processes using them | EXXONMOBIL CHEMICAL PATENTS INC. | 2002-08-22 | — | — | US | disclosed |
| US-20020111265-A1 | GROUP-15 CATIONIC COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS | EXXONMOBIL CHEMICAL PATENTS INC. | 2002-08-15 | — | — | US | disclosed |