Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | ICMT | O60725 | 2/20 | 0.42 |
| ▸ | ALB | P02768 | 2/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5716084 | 1.00 | NPC1 (0.47) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL25227860 | 0.88 | NPC1 (0.53) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL25270420 | 0.88 | NPC1 (0.53) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL25224466 | 0.88 | NPC1 (0.53) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL25229294 | 0.88 | NPC1 (0.53) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL25278096 | 0.88 | NPC1 (0.53) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL25224593 | 0.88 | NPC1 (0.53) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL25276956 | 0.88 | NPC1 (0.53) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL25224460 | 0.88 | NPC1 (0.53) | NPC1JAK2RAB9APAX8KCNH2 | |
| SCHEMBL25227148 | 0.88 | NPC1 (0.53) | NPC1JAK2RAB9APAX8KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6822057-B2 | OLEFIN POLYMERIZATION CATALYST SYSTEM IS A REACTION PRODUCT OF A METALLOCENES AND A COCATALYST CONTAINING FLUOROARYL SUBSTITUTED SECONDARY AMINE OR PHSOPHINE COMPOUND AND AN ANION CONTAINING GROUP 13 ELEMENT WHICH IS NONCOORDINATIG | EXXON MOBIL CHEMICAL PATENTS INC. | 2004-11-23 | — | — | US | disclosed |
| US-6489480-B2 | COORDINATION POLYMERIZATION CATALYST FOR ALPHA-OLEFINS | EXXONMOBIL CHEMICAL PATENTS INC. | 2002-12-03 | — | — | US | disclosed |
| US-20020115806-A1 | Olefin polymerization catalysts derived from Group-15 cationic compounds and processes using them | EXXONMOBIL CHEMICAL PATENTS INC. | 2002-08-22 | — | — | US | disclosed |
| US-20020111265-A1 | GROUP-15 CATIONIC COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS | EXXONMOBIL CHEMICAL PATENTS INC. | 2002-08-15 | — | — | US | disclosed |