Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSF1 | Q00613 | 1/20 | 0.67 |
| ▸ | ROCK2 | O75116 | 7/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6787116 | 0.89 | HSF1 (0.70) | HSF1ROCK2ROCK1PDGFRBPDGFRA | |
| SCHEMBL9985298 | 0.85 | HSF1 (0.62) | HSF1ROCK2ROCK1PIK3CAPDGFRB | |
| SCHEMBL9985304 | 0.85 | HSF1 (0.65) | HSF1ROCK2ROCK1PIK3CAPIK3CD | |
| SCHEMBL6786464 | 0.82 | HSF1 (0.60) | HSF1ROCK1PDGFRBPDGFRAEGFR | |
| SCHEMBL9985287 | 0.81 | HSF1 (0.67) | HSF1ROCK2ROCK1EGFR | |
| SCHEMBL6783318 | 0.81 | HSF1 (1.00) | HSF1ROCK2ROCK1EGFR | |
| SCHEMBL29695497 | 0.81 | HSF1 (1.00) | HSF1ROCK2ROCK1EGFR | |
| SCHEMBL29380539 | 0.81 | HSF1 (1.00) | HSF1ROCK2ROCK1EGFR | |
| SCHEMBL9986111 | 0.79 | HSF1 (0.52) | HSF1PDGFRBPDGFRAEGFR | |
| SCHEMBL6789472 | 0.79 | HSF1 (0.74) | HSF1ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1610667-A | 3-nitropyridine derivaives and the pharmaceutical compositions containing said derivatives | DONG WHA PHARM IND CO LTD (KR) | 2005-04-27 | — | — | CN | disclosed |
| US-6743795-B1 | INHIBITORS FOR HEPATITIS B AND ACQUIRED IMMUNE DEFICIENCY SYNDROME (AIDS) BECAUSE THEY INTERFERE WITH REMOVAL OF RNA STRAND FROM RNA-DNA HYBRID FORMED DURING THE REVERSE TRANSCRIPTION OF VIRAL RNA TO DNA | DONG WHA PHARM. IND. CO. LTD. (KR) | 2004-06-01 | — | — | US | disclosed |