⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4267378 | 0.71 | — | — | |
| SCHEMBL9587810 | 0.69 | GSK3B (0.37) | — | |
| SCHEMBL31468808 | 0.65 | — | — | |
| SCHEMBL2937688 | 0.65 | — | — | |
| SCHEMBL1127854 | 0.65 | — | — | |
| SCHEMBL1304475 | 0.65 | — | — | |
| SCHEMBL36967 | 0.65 | — | — | |
| SCHEMBL19900692 | 0.65 | — | — | |
| SCHEMBL75166 | 0.65 | — | — | |
| SCHEMBL996566 | 0.65 | GSK3A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2365969-B1 | Novel anti-biofilm agents | YISSUM RES DEV CO (IL) | 2017-03-22 | — | — | EP | disclosed |
| US-8865909-B2 | Anti-biofilm agents | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2014-10-21 | — | — | US | disclosed |
| US-20110281921-A1 | NOVEL ANTI-BIOFILM AGENTS | HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT LTD. (IL) | 2011-11-17 | — | — | US | disclosed |
| EP-2365969-A1 | Novel anti-biofilm agents | Yissum Research Development Company of The Hebrew University of Jerusalem (IL) | 2011-09-21 | — | — | EP | disclosed |
| WO-2010058402-A1 | NOVEL ANTI-BIOFILM AGENTS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2010-05-27 | — | — | WO | disclosed |