Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 3/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8022236 | 0.85 | POLB (0.49) | HPGDCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL31264414 | 0.85 | POLB (0.49) | HPGDCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8022234 | 0.85 | POLB (0.49) | HPGDCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6700689 | 0.85 | CYP1A2 (0.47) | HPGDCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6700693 | 0.85 | CYP1A2 (0.47) | HPGDCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11520462 | 0.84 | HPGD (0.44) | HPGDCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11520466 | 0.84 | HPGD (0.44) | HPGDCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11520468 | 0.84 | NPC1 (0.50) | HPGDCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6781009 | 0.84 | HIF1A (0.46) | HPGDCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10478000 | 0.83 | TSHR (0.45) | HPGDCYP2C19MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6730705-B1 | USE AS AGENTS FOR COMBATING PESTS | BAYER AKTIENGESELLSCHAFT (DE) | 2004-05-04 | — | — | US | disclosed |
| US-6130251-A | USE AS AGENTS FOR COMBATING PESTS. | BAYER AKTIENGESELLSCHAFT (DE) | 2000-10-10 | — | — | US | disclosed |