SCHEMBL6790794

SCHEMBL6790794

C#Cc1ccc2cc(S(=O)(=O)N3CCN(C(=O)N4CCC5=C(N4)SCN5)CC3)sc2c1

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
F10 P00742 10/20 0.37
MAPT P10636 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6729054 0.87 F10 (0.50) F10
SCHEMBL6729517 0.85 F10 (0.37) F10MAPTL3MBTL1
SCHEMBL6729206 0.84 F10 (0.35) F10
SCHEMBL6725267 0.83 F10 (0.34) F10
SCHEMBL6728747 0.82 F10 (0.46) F10
SCHEMBL6735146 0.82 F10 (0.46) F10
SCHEMBL6726237 0.82 F10 (0.37) F10
SCHEMBL6738149 0.81 F10 (0.36) F10
SCHEMBL6733506 0.77 F10 (0.36) F10
SCHEMBL6726031 0.72 F10 (0.42) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6747023-B1 INHIBITORS FOR ACTIVATED COAGULATION FACTOR X, COAGULATION SUPPRESSORS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-06-08 US disclosed
EP-1104754-A1 NOVEL SULFONYL DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2001-06-06 EP disclosed