Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | PPARD | Q03181 | 3/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 5/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6736082 | 0.89 | PPARG (0.41) | PPARGPPARAPPARDOPRK1ALDH1A1 | |
| SCHEMBL6733146 | 0.87 | PPARG (0.45) | PPARGPPARAPPARDOPRK1ALDH1A1 | |
| SCHEMBL6731589 | 0.86 | PPARG (0.41) | PPARGPPARAPPARDOPRK1ALDH1A1 | |
| SCHEMBL6728741 | 0.85 | PPARG (0.41) | PPARGPPARAPPARDALDH1A1KDM4E | |
| SCHEMBL6733597 | 0.85 | PPARG (0.38) | PPARGPPARAPPARDOPRK1ALDH1A1 | |
| SCHEMBL6725421 | 0.84 | PPARG (0.43) | PPARGPPARAPPARDOPRK1ALDH1A1 | |
| SCHEMBL6730522 | 0.83 | PPARG (0.39) | PPARGPPARAPPARDOPRK1ALDH1A1 | |
| SCHEMBL6737263 | 0.83 | PPARG (0.39) | PPARGPPARAPPARDALDH1A1KDM4E | |
| SCHEMBL6725126 | 0.82 | PPARG (0.41) | PPARGPPARAPPARDOPRK1ALDH1A1 | |
| SCHEMBL6732137 | 0.82 | PPARG (0.44) | PPARGPPARAPPARDALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6747023-B1 | INHIBITORS FOR ACTIVATED COAGULATION FACTOR X, COAGULATION SUPPRESSORS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-06-08 | — | — | US | disclosed |
| EP-1104754-A1 | NOVEL SULFONYL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-06-06 | — | — | EP | disclosed |