Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6819339 | 0.86 | PBRM1 (0.55) | PBRM1MAPTGAAKDM4EKMT2A | |
| SCHEMBL11147848 | 0.84 | KDM4E (0.68) | PBRM1MAPTGAAKDM4EKMT2A | |
| SCHEMBL17008169 | 0.82 | AKR1C3 (0.63) | MAPTGAAKMT2AMEN1USP2 | |
| 5-Amino-2-Benzoylbenzoic Acid SCHEMBL8999371 | 0.81 | AKR1C3 (0.62) | PBRM1MAPTGAAKDM4EKMT2A | |
| 5-Amino-2-Benzoylbenzoic Acid SCHEMBL31333092 | 0.81 | AKR1C3 (0.62) | PBRM1MAPTGAAKDM4EKMT2A | |
| SCHEMBL5312884 | 0.80 | MAPT (0.68) | PBRM1MAPTGAAKDM4EKMT2A | |
| SCHEMBL4351040 | 0.79 | CYP2C9 (0.65) | PBRM1MAPTGAAKDM4EKMT2A | |
| SCHEMBL29530480 | 0.79 | MAPT (0.66) | PBRM1MAPTGAAKDM4EKMT2A | |
| SCHEMBL30341893 | 0.79 | CYP2C9 (0.65) | PBRM1MAPTGAAKDM4EKMT2A | |
| SCHEMBL3179244 | 0.79 | MAPT (0.66) | PBRM1MAPTGAAKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082585-A1 | Prodrugs of substituted polycyclic compounds useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082585-A1 | Prodrugs of substituted polycyclic compounds useful for selective inhibition of the coagulation cascade | TFPI, F2, PLG | PBRM1 2306/4885MAPT 4848/4885GAA 1146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.