Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 16/20 | 0.51 |
| ▸ | CDK2 | P24941 | 16/20 | 0.51 |
| ▸ | CCNA1 | P78396 | 16/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6793922 | 0.91 | CCNA2 (0.50) | CCNA2CDK2CCNA1ALDH1A1MEN1 | |
| SCHEMBL6793926 | 0.89 | CCNA2 (0.44) | CCNA2CDK2CCNA1 | |
| SCHEMBL6792636 | 0.85 | CCNA2 (0.49) | CCNA2CDK2CCNA1ALDH1A1MEN1 | |
| SCHEMBL6793829 | 0.85 | CCNA2 (0.45) | CCNA2CDK2CCNA1 | |
| Hydrochloric Acid SCHEMBL6786608 | 0.85 | CCNA2 (0.48) | CCNA2CDK2CCNA1ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL6792449 | 0.85 | CCNA2 (0.52) | CCNA2CDK2CCNA1 | |
| SCHEMBL5233247 | 0.85 | CCNA2 (0.48) | CCNA2CDK2CCNA1ALDH1A1MEN1 | |
| SCHEMBL6788502 | 0.84 | CCNA2 (0.48) | CCNA2CDK2CCNA1ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL5230409 | 0.84 | CCNA2 (0.48) | CCNA2CDK2CCNA1ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL6798149 | 0.84 | CCNA2 (0.48) | CCNA2CDK2CCNA1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040127492-A1 | Cyclic pyrazoles for the inhibition of mitogen activated protein kinase-activated protein kinase-2 | PHARMACIA CORPORATION | 2004-07-01 | — | — | US | claimed |
| US-20040127492-A1 | Cyclic pyrazoles for the inhibition of mitogen activated protein kinase-activated protein kinase-2 | PHARMACIA CORPORATION | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127492-A1 | Cyclic pyrazoles for the inhibition of mitogen activated protein kinase-activated protein kinase-2 | MKNK2, MAPKAPK2, MAP3K2 | CCNA2 270/4885CDK2 29/4885CCNA1 527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.