Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK6 | Q92876 | 2/20 | 0.46 |
| ▸ | KLK8 | O60259 | 1/20 | 0.46 |
| ▸ | KLK14 | Q9P0G3 | 1/20 | 0.46 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 5/20 | 0.44 |
| ▸ | F2 | P00734 | 9/20 | 0.44 |
| ▸ | F10 | P00742 | 8/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.42 |
| ▸ | PLG | P00747 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6792389 | 0.99 | KLK6 (0.46) | KLK6KLK8KLK14KLK5PLAU | |
| SCHEMBL6793200 | 0.92 | F2 (0.44) | KLK6KLK8KLK14KLK5PLAU | |
| Hydrochloric Acid SCHEMBL6793195 | 0.91 | F2 (0.43) | KLK6KLK8KLK14KLK5PLAU | |
| SCHEMBL6783458 | 0.84 | KLK8 (0.42) | KLK6KLK8KLK14KLK5PLAU | |
| SCHEMBL6781492 | 0.83 | KLK6 (0.45) | KLK6KLK8KLK14KLK5PLAU | |
| Hydrochloric Acid SCHEMBL6783450 | 0.83 | KLK8 (0.42) | KLK6KLK8KLK14KLK5PLAU | |
| Hydrochloric Acid SCHEMBL6781488 | 0.82 | KLK6 (0.45) | KLK6KLK8KLK14KLK5PLAU | |
| SCHEMBL6782996 | 0.82 | KLK8 (0.43) | KLK6KLK8KLK14KLK5PLAU | |
| SCHEMBL6784836 | 0.82 | KLK8 (0.41) | KLK6KLK8KLK14KLK5PLAU | |
| Hydrochloric Acid SCHEMBL6782992 | 0.81 | KLK8 (0.42) | KLK6KLK8KLK14KLK5PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699862-B1 | ANTITUMOR | PFIZER INC. | 2004-03-02 | — | — | US | claimed |