SCHEMBL6792698

SCHEMBL6792698

FCP(CF)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
ESR1 P03372 4/20 0.36
ESR2 Q92731 4/20 0.36
CALM1 P0DP23 1/20 0.33
KDM4E B2RXH2 2/20 0.32
GAA P10253 1/20 0.32
CYP19A1 P11511 1/20 0.32
ALDH1A1 P00352 5/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C19 P33261 1/20 0.32
MAPT P10636 1/20 0.32
TSHR P16473 4/20 0.30
IDO1 P14902 1/20 0.30
TP53 P04637 1/20 0.30
LOXL2 Q9Y4K0 1/20 0.30
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6789951 0.84 TDP1 (0.39) CYP3A4TDP1ESR1ESR2KDM4E
SCHEMBL6786715 0.77 TSHR (0.35) CYP3A4TDP1ESR1KDM4ETSHR
SCHEMBL1465059 0.73 TDP1 (0.45) CYP3A4TDP1ESR1ESR2CALM1
SCHEMBL231466 0.73 CYP3A4 (0.45) CYP3A4TDP1ESR1ESR2CALM1
SCHEMBL6792694 0.71 CYP3A4 (0.38) CYP3A4TDP1ESR1ESR2ALDH1A1
SCHEMBL11551492 0.71 CYP3A4 (0.43) CYP3A4TDP1ESR1ESR2CALM1
SCHEMBL4257325 0.71 CYP3A4 (0.43) CYP3A4TDP1ESR1ESR2CALM1
SCHEMBL5588513 0.71 CYP3A4 (0.43) CYP3A4TDP1ESR1ESR2CALM1
SCHEMBL4250554 0.71 TDP1 (0.43) CYP3A4TDP1CALM1ALDH1A1TSHR
SCHEMBL29598351 0.71 CYP3A4 (0.43) CYP3A4TDP1ESR1ESR2CALM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6822057-B2 OLEFIN POLYMERIZATION CATALYST SYSTEM IS A REACTION PRODUCT OF A METALLOCENES AND A COCATALYST CONTAINING FLUOROARYL SUBSTITUTED SECONDARY AMINE OR PHSOPHINE COMPOUND AND AN ANION CONTAINING GROUP 13 ELEMENT WHICH IS NONCOORDINATIG EXXON MOBIL CHEMICAL PATENTS INC. 2004-11-23 US disclosed
US-6489480-B2 COORDINATION POLYMERIZATION CATALYST FOR ALPHA-OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2002-12-03 US disclosed
US-20020115806-A1 Olefin polymerization catalysts derived from Group-15 cationic compounds and processes using them EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-22 US disclosed
US-20020111265-A1 GROUP-15 CATIONIC COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-15 US disclosed