Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 19/20 | 0.68 |
| ▸ | F3 | P13726 | 7/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8363138 | 0.93 | F7 (0.68) | F7F3PRSS1PRSS2PRSS3 | |
| SCHEMBL6793052 | 0.92 | F7 (0.60) | F7F3PRSS1PRSS2PRSS3 | |
| SCHEMBL6793049 | 0.92 | F7 (0.60) | F7F3PRSS1PRSS2PRSS3 | |
| SCHEMBL6793117 | 0.87 | F7 (0.60) | F7F3PRSS1PRSS2PRSS3 | |
| SCHEMBL6793137 | 0.86 | F7 (0.60) | F7F3PRSS1PRSS2PRSS3 | |
| SCHEMBL6793144 | 0.86 | F7 (0.60) | F7F3PRSS1PRSS2PRSS3 | |
| SCHEMBL8360246 | 0.85 | F7 (0.73) | F7F3PRSS1F2 | |
| SCHEMBL8363577 | 0.85 | F7 (0.73) | F7F3PRSS1F2 | |
| SCHEMBL6793680 | 0.85 | F7 (0.59) | F7F3PRSS1PRSS2PRSS3 | |
| SCHEMBL6793690 | 0.85 | F7 (0.59) | F7F3PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040106626-A1 | 6-Membered unsaturated heterocyclic compounds useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION | 2004-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106626-A1 | 6-Membered unsaturated heterocyclic compounds useful for selective inhibition of the coagulation cascade | TFPI, F2, TFPI2 | F7 20/4885F3 16/4885PRSS1 68/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.