Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 18/20 | 0.58 |
| ▸ | GRM3 | Q14832 | 18/20 | 0.58 |
| ▸ | GRM6 | O15303 | 3/20 | 0.57 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.57 |
| ▸ | GRM8 | O00222 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6796401 | 0.89 | GRM2 (0.70) | GRM2GRM3GRM6GRM4GRM8 | |
| SCHEMBL6787888 | 0.88 | GRM2 (0.73) | GRM2GRM3GRM6GRM4GRM8 | |
| SCHEMBL6795022 | 0.88 | GRM2 (0.60) | GRM2GRM3GRM6GRM4GRM8 | |
| SCHEMBL6788529 | 0.87 | GRM2 (0.72) | GRM2GRM3GRM6GRM4GRM8 | |
| SCHEMBL6790536 | 0.87 | GRM2 (0.72) | GRM2GRM3GRM6GRM4GRM8 | |
| SCHEMBL6793748 | 0.86 | GRM2 (0.73) | GRM2GRM3GRM6GRM4GRM8 | |
| SCHEMBL6795693 | 0.83 | GRM2 (0.78) | GRM2GRM3GRM6GRM4GRM8 | |
| SCHEMBL6794929 | 0.83 | GRM2 (0.61) | GRM2GRM3GRM6GRM4GRM8 | |
| SCHEMBL6789434 | 0.83 | GRM2 (0.61) | GRM2GRM3GRM6GRM4GRM8 | |
| SCHEMBL6794260 | 0.81 | GRM2 (0.63) | GRM2GRM3GRM6GRM4GRM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116489-A1 | Synthetic excitatory amino acids | ELI LILLY AND COMPANY | 2004-06-17 | — | — | US | disclosed |