Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.59 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.59 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.59 |
| ▸ | PPARA | Q07869 | 11/20 | 0.58 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | PLAT | P00750 | 1/20 | 0.50 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6794649 | 1.00 | CSNK2A2 (0.59) | CSNK2A2CSNK2BCSNK2A1PPARAPLCG2 | |
| SCHEMBL10897969 | 0.82 | CSNK2A2 (0.65) | CSNK2A2CSNK2BCSNK2A1PLCG2ALDH1A1 | |
| SCHEMBL6795744 | 0.80 | CSNK2A2 (0.79) | CSNK2A2CSNK2BCSNK2A1PLCG2ALDH1A1 | |
| SCHEMBL6795748 | 0.80 | CSNK2A2 (0.79) | CSNK2A2CSNK2BCSNK2A1PLCG2ALDH1A1 | |
| SCHEMBL13521553 | 0.80 | PLCG2 (0.57) | CSNK2A2CSNK2BCSNK2A1PLCG2ALDH1A1 | |
| SCHEMBL10599303 | 0.77 | KMT2A (0.69) | CSNK2A2CSNK2BCSNK2A1PLCG2ALDH1A1 | |
| SCHEMBL15421781 | 0.77 | KMT2A (0.69) | CSNK2A2CSNK2BCSNK2A1PLCG2ALDH1A1 | |
| SCHEMBL6796550 | 0.76 | MEN1 (0.67) | CSNK2A2CSNK2BCSNK2A1PLCG2ALDH1A1 | |
| SCHEMBL6796548 | 0.76 | MEN1 (0.67) | CSNK2A2CSNK2BCSNK2A1PLCG2ALDH1A1 | |
| SCHEMBL15421524 | 0.76 | MEN1 (0.67) | CSNK2A2CSNK2BCSNK2A1PLCG2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040180943-A1 | Oxazolone analogs as amyloid aggregation inhibitors and for the treatment of alzheimer's disease and disorders related to amyloidosis | WARNER-LAMBERT COMPANY LLC | 2004-09-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040180943-A1 | Oxazolone analogs as amyloid aggregation inhibitors and for the treatment of alzheimer's disease and disorders related to amyloidosis | APP, PSEN1, PSEN2 | CSNK2A2 1982/4885CSNK2B 1874/4885CSNK2A1 1986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.