Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 10/20 | 0.72 |
| ▸ | HTR2A | P28223 | 7/20 | 0.72 |
| ▸ | HTR2C | P28335 | 7/20 | 0.72 |
| ▸ | HTR2B | P41595 | 7/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5348386 | 0.89 | HRH2 (0.77) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL5345961 | 0.88 | HRH2 (0.68) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL5350397 | 0.86 | HTR2A (0.74) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL4051105 | 0.85 | HRH2 (0.86) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL5347380 | 0.85 | HRH2 (0.78) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL4056106 | 0.84 | HRH2 (0.82) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL5344198 | 0.84 | HRH2 (1.00) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL5358193 | 0.84 | HTR2A (0.77) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL5349987 | 0.84 | HTR2A (1.00) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL5343555 | 0.83 | HRH2 (0.70) | HRH2HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116471-A1 | Indolylpiperidine derivatives as antihistaminic aand antiallergic agents | ALMIRALL PRODESFARMA S.A. (ES) | 2004-06-17 | — | — | US | disclosed |