Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | CBX7 | O95931 | 2/20 | 0.45 |
| ▸ | CDYL | Q9Y232 | 2/20 | 0.45 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.43 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 4/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.37 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.37 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6787357 | 0.84 | IDO1 (0.50) | IDO1CBX7CDYLCDYL2CDY1; CDY1B | |
| SCHEMBL2495393 | 0.78 | KMT2A (0.57) | IDO1CBX7CDYLCDYL2CDY1; CDY1B | |
| SCHEMBL2499035 | 0.77 | KMT2A (0.53) | IDO1CBX7CDYLCDYL2CDY1; CDY1B | |
| SCHEMBL4590131 | 0.77 | KMT2A (0.56) | IDO1CBX7CDYLCDYL2CDY1; CDY1B | |
| SCHEMBL2495396 | 0.77 | CBX7 (0.48) | IDO1CBX7CDYLCDYL2CDY1; CDY1B | |
| SCHEMBL5354644 | 0.76 | POLB (0.46) | IDO1CBX7CDYLCDYL2CDY1; CDY1B | |
| SCHEMBL2499637 | 0.76 | POLB (0.51) | IDO1CBX7CDYLCDYL2CDY1; CDY1B | |
| SCHEMBL1464565 | 0.75 | KMT2A (0.72) | IDO1CBX7CDYLCDYL2CDY1; CDY1B | |
| SCHEMBL2493174 | 0.74 | KMT2A (0.55) | IDO1CBX7CDYLCDYL2CDY1; CDY1B | |
| SCHEMBL2498528 | 0.74 | BRD4 (0.57) | IDO1CBX7CDYLKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040180878-A1 | Phenylsulfonyl-1,3-dihydro-2h-indole-2-one derivatives, their preparation and their therapeutic use | SANOFI-AVENTIS (FR) | 2004-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040180878-A1 | Phenylsulfonyl-1,3-dihydro-2h-indole-2-one derivatives, their preparation and their therapeutic use | AVPR2, AVPR1A, AVPR1B | IDO1 86/4885CBX7 4457/4885CDYL 3055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.