SCHEMBL679489

SCHEMBL679489

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nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9694838 1.00
SCHEMBL2675782 1.00
SCHEMBL7804 1.00
SCHEMBL8015149 1.00
SCHEMBL1890701 1.00
SCHEMBL8661925 1.00
SCHEMBL131783 1.00
SCHEMBL21774 1.00
SCHEMBL8420181 1.00
SCHEMBL11234658 1.00

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4221907-A COMPLEMENT INHIBITORS AMERICAN CYANAMID COMPANY (US) 1980-09-09 US claimed
WO-2024076934-A2 COMPOSITIONS AND METHODS FOR MODULATION OF CFTR CYSTIC FIBROSIS FOUNDATION (US) 2024-04-11 WO disclosed
WO-2024026122-A2 COMPOUNDS FOR TREATMENT OF CONDITIONS AND DISEASES STOKE THERAPEUTICS, INC. (US) 2024-02-01 WO disclosed
US-20240033358-A1 COMBINATION THERAPIES WITH CHIMERIC ANTIGEN RECEPTOR (CAR)-EXPRESSING CELLS NOVARTIS AG (CH) 2024-02-01 US disclosed
US-20230116704-A1 ANTISENSE OLIGOMERS FOR TREATMENT OF CONDITIONS AND DISEASES STOKE THERAPEUTICS, INC. 2023-04-13 US disclosed
CN-115087452-A Antisense oligomers for the treatment of conditions and diseases 斯托克制药公司 2022-09-20 CN disclosed
WO-2021113541-A1 ANTISENSE OLIGOMERS FOR TREATMENT OF CONDITIONS AND DISEASES STOKE THERAPEUTICS, INC. (US) 2021-06-10 WO disclosed
US-20150056186-A1 COMBINATION THERAPY OF A TYPE II ANTI-CD20 ANTIBODY WITH AN ANTI-BCL-2 ACTIVE AGENT HOFFMANN-LA ROCHE INC. (US) 2015-02-26 US disclosed
US-20140004104-A1 COMBINATION THERAPY OF A TYPE II ANTI-CD20 ANTIBODY WITH AN ANTI-BCL-2 ACTIVE AGENT HOFFMANN-LA ROCHE INC. (US) 2014-01-02 US disclosed
EP-2604277-A1 Combination therapy of a type II anti-CD20 antibody with an anti-Bcl-2 active agent Roche Glycart AG (CH) 2013-06-19 EP disclosed
US-20120276085-A1 COMBINATION THERAPY OF A TYPE II ANTI-CD20 ANTIBODY WITH AN ANTI-BCL-2 ACTIVE AGENT Hoffman-La Roche. Inc. (US) 2012-11-01 US disclosed
US-20110287006-A1 COMBINATION THERAPY OF A TYPE II ANTI-CD20 ANTIBODY WITH AN ANTI-BCL-2 ACTIVE AGENT Hoffman-La Roche. Inc. (US) 2011-11-24 US disclosed
US-20110086025-A1 Combination Therapy of a Type II Anti-CD20 Antibody with an Anti-BCL-2 Active Agent Hoffman-La Roche. Inc. (US) 2011-04-14 US disclosed
EP-2203185-A1 COMBINATION THERAPY OF A TYPE II ANTI-CD20 ANTIBODY WITH AN ANTI-BCL-2 ACTIVE AGENT Roche Glycart AG (CH) 2010-07-07 EP disclosed
WO-2009049841-A1 COMBINATION THERAPY OF A TYPE II ANTI-CD20 ANTIBODY WITH AN ANTI-BCL-2 ACTIVE AGENT F. HOFFMANN-LA ROCHE AG (CH) 2009-04-23 WO disclosed
US-20090098118-A1 COMBINATION THERAPY OF A TYPE II ANTI-CD20 ANTIBODY WITH AN ANTI-BCL-2 ACTIVE AGENT ROCHE GLYCART AG (CH) 2009-04-16 US disclosed
US-4232150-A COMPLEMENT INHIBITORS AMERICAN CYANAMID COMPANY (US) 1980-11-04 US disclosed
US-4221907-A COMPLEMENT INHIBITORS AMERICAN CYANAMID COMPANY (US) 1980-09-09 US disclosed