Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 9/20 | 0.54 |
| ▸ | CDK2 | P24941 | 9/20 | 0.54 |
| ▸ | CCNA1 | P78396 | 9/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5727685 | 1.00 | CCNA2 (0.54) | CCNA2CDK2CCNA1HDAC1HPGD | |
| SCHEMBL6790358 | 1.00 | CCNA2 (0.54) | CCNA2CDK2CCNA1HDAC1HPGD | |
| SCHEMBL5769663 | 0.85 | CCNA2 (0.53) | CCNA2CDK2CCNA1HDAC1HRH3 | |
| SCHEMBL5726470 | 0.85 | CCNA2 (0.53) | CCNA2CDK2CCNA1HDAC1HRH3 | |
| SCHEMBL5727140 | 0.85 | CCNA2 (0.53) | CCNA2CDK2CCNA1HDAC1HRH3 | |
| SCHEMBL24451811 | 0.80 | CCNA2 (0.46) | CCNA2CDK2CCNA1HDAC1ALDH1A1 | |
| SCHEMBL6796684 | 0.79 | CCNA2 (0.53) | CCNA2CDK2CCNA1HPGDALDH1A1 | |
| SCHEMBL6788871 | 0.79 | CCNA2 (0.53) | CCNA2CDK2CCNA1HPGDALDH1A1 | |
| SCHEMBL5726513 | 0.79 | CCNA2 (0.53) | CCNA2CDK2CCNA1HPGDALDH1A1 | |
| SCHEMBL6784455 | 0.76 | HIF1A (0.54) | CCNA2CDK2CCNA1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040235919-A1 | Phenylacetamido-thiazole derivatives, process for the preparation and their use as antitumor agents | PFIZER ITALIA S.R.I. (IT) | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235919-A1 | Phenylacetamido-thiazole derivatives, process for the preparation and their use as antitumor agents | CDK2, CDK1, CDKN1A | CCNA2 31/4885CDK2 1/4885CCNA1 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.