Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 20/20 | 0.77 |
| ▸ | BCL2 | P10415 | 15/20 | 0.77 |
| ▸ | ALB | P02768 | 1/20 | 0.72 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6799848 | 0.98 | BCL2L1 (0.79) | BCL2L1BCL2ALBBCL2L2 | |
| SCHEMBL6798865 | 0.96 | BCL2L1 (0.73) | BCL2L1BCL2ALBBCL2L2 | |
| SCHEMBL6795001 | 0.95 | BCL2L1 (0.86) | BCL2L1BCL2ALBBCL2L2 | |
| SCHEMBL6795003 | 0.95 | BCL2L1 (0.86) | BCL2L1BCL2ALBBCL2L2 | |
| SCHEMBL6791105 | 0.92 | BCL2L1 (0.78) | BCL2L1BCL2ALBBCL2L2 | |
| SCHEMBL6791110 | 0.92 | BCL2L1 (0.78) | BCL2L1BCL2ALBBCL2L2 | |
| SCHEMBL685148 | 0.92 | BCL2L1 (0.88) | BCL2L1BCL2ALBBCL2L2 | |
| SCHEMBL4465505 | 0.90 | BCL2L1 (0.88) | BCL2L1BCL2ALBBCL2L2 | |
| SCHEMBL4477794 | 0.89 | BCL2L1 (0.86) | BCL2L1BCL2ALBBCL2L2 | |
| SCHEMBL2943969 | 0.88 | BCL2L1 (0.74) | BCL2L1BCL2ALBBCL2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720338-B2 | BCL-X1 INHIBITING COMPOSITIONS AND METHODS OF PROMOTING APOPTOSIS IN A MAMMAL | ABBOTT LABORATORIES | 2004-04-13 | — | — | US | claimed |