Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.53 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.53 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | CBS | P35520 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6796766 | 1.00 | CSNK2A2 (0.53) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A | |
| SCHEMBL6800601 | 0.92 | CSNK2A2 (0.64) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A | |
| SCHEMBL6800599 | 0.92 | CSNK2A2 (0.64) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A | |
| SCHEMBL6792564 | 0.86 | CSNK2A2 (0.59) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A | |
| SCHEMBL6792570 | 0.86 | CSNK2A2 (0.59) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A | |
| SCHEMBL6794318 | 0.86 | CSNK2A2 (0.72) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A | |
| SCHEMBL6794321 | 0.86 | CSNK2A2 (0.72) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A | |
| SCHEMBL6796387 | 0.84 | CSNK2A2 (0.56) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A | |
| SCHEMBL6796391 | 0.84 | CSNK2A2 (0.56) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A | |
| SCHEMBL6795960 | 0.83 | CSNK2A2 (0.51) | CSNK2A2CSNK2BCSNK2A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040180943-A1 | Oxazolone analogs as amyloid aggregation inhibitors and for the treatment of alzheimer's disease and disorders related to amyloidosis | WARNER-LAMBERT COMPANY LLC | 2004-09-16 | — | — | US | claimed |
| US-20040180943-A1 | Oxazolone analogs as amyloid aggregation inhibitors and for the treatment of alzheimer's disease and disorders related to amyloidosis | WARNER-LAMBERT COMPANY LLC | 2004-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040180943-A1 | Oxazolone analogs as amyloid aggregation inhibitors and for the treatment of alzheimer's disease and disorders related to amyloidosis | APP, PSEN1, PSEN2 | CSNK2A2 1982/4885CSNK2B 1874/4885CSNK2A1 1986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.