SCHEMBL6797157

SCHEMBL6797157

C1CCC(=C2CCCC2)CC1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 2/20 0.43
TRIM33 Q9UPN9 2/20 0.43
ALDH1A1 P00352 2/20 0.43
TSHR P16473 1/20 0.35
CASP1 P29466 1/20 0.35
HPGD P15428 2/20 0.33
HTT P42858 1/20 0.33
MEN1 O00255 1/20 0.31
MAPT P10636 1/20 0.31
ALOX15 P16050 1/20 0.31
ALOX12 P18054 1/20 0.31
BLM P54132 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31
NOS3 P29474 3/20 0.30
NOS1 P29475 3/20 0.30
NOS2 P35228 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15703279 1.00 TRIM24 (0.43) TRIM24TRIM33ALDH1A1TSHRCASP1
SCHEMBL1628153 1.00 TRIM24 (0.43) TRIM24TRIM33ALDH1A1TSHRCASP1
SCHEMBL4840007 1.00 TRIM24 (0.43) TRIM24TRIM33ALDH1A1TSHRCASP1
SCHEMBL11077890 1.00 TRIM24 (0.43) TRIM24TRIM33ALDH1A1TSHRCASP1
SCHEMBL365601 1.00 TRIM24 (0.43) TRIM24TRIM33ALDH1A1TSHRCASP1
SCHEMBL1332943 1.00 TRIM24 (0.43) TRIM24TRIM33ALDH1A1TSHRCASP1
SCHEMBL502191 1.00 TRIM24 (0.43) TRIM24TRIM33ALDH1A1TSHRCASP1
SCHEMBL8653747 1.00 TRIM24 (0.43) TRIM24TRIM33ALDH1A1TSHRCASP1
SCHEMBL11067883 1.00 TRIM24 (0.43) TRIM24TRIM33ALDH1A1TSHRCASP1
SCHEMBL11077885 1.00 TRIM24 (0.43) TRIM24TRIM33ALDH1A1TSHRCASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4337336-A Derivative of kanamycin A and a process for the preparation thereof ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1982-06-29 US claimed
CN-109725508-A Polyarylate resin and Electrophtography photosensor 京瓷办公信息系统株式会社 2019-05-07 CN disclosed
US-9459533-B2 Polymer composition, photoresist comprising the polymer composition, and coated article comprising the photoresist DOW GLOBAL TECHNOLOGIES LLC (US) 2016-10-04 US disclosed
US-20140194576-A1 RUBBER COMPOSITION, CROSSLINKED RUBBER COMPOSITION, PNEUMATIC TIRE, AND METHOD FOR PRODUCING ISOBUTYLENE POLYMER JX NIPPON OIL & ENERGY CORPORATION (JP) 2014-07-10 US disclosed
EP-2733172-A1 RUBBER COMPOSITION, CROSSLINKED RUBBER COMPOSITION, PNEUMATIC TIRE, AND METHOD FOR PRODUCING ISOBUTYLENE POLYMER JX Nippon Oil & Energy Corporation (JP) 2014-05-21 EP disclosed
US-20140004464-A1 POLYMER COMPOSITION, PHOTORESIST COMPRISING THE POLYMER COMPOSITION, AND COATED ARTICLE COMPRISING THE PHOTORESIST ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2014-01-02 US disclosed
CN-100558696-C The diine material that is used for Application in Sensing 3M INNOVATIVE PROPERTIES CO (US) 2009-11-11 CN disclosed
CN-1745057-A Diyne materials for sensing applications 3M INNOVATIVE PROPERTIES CO (US) 2006-03-08 CN disclosed
US-20040063764-A1 Halogen compounds having thrombopoietin receptor agonism SHIONOGI & CO., LTD. (JP) 2004-04-01 US disclosed
EP-1354880-A1 HALOGEN COMPOUNDS HAVING THROMBOPOIETIN RECEPTOR AGONISM SHIONOGI & CO., LTD. (JP) 2003-10-22 EP disclosed
EP-0805824-B1 A SUPPORTED CATALYTIC ACTIVATOR GRACE W R & CO (US) 2002-04-24 EP disclosed
EP-0830385-A1 HALOGENATED SUPPORTS AND SUPPORTED ACTIVATORS W.R. Grace & Co.-Conn. (US) 1998-03-25 EP disclosed
WO-1996040796-A1 HALOGENATED SUPPORTS AND SUPPORTED ACTIVATORS W.R. GRACE & CO.-CONN. (US) 1996-12-19 WO disclosed
WO-1996013532-A1 IN SITU DEHYDROXYLATION OF SUPPORTS AND PREPARATION OF SUPPORTED METALLOCENE POLYOLEFIN CATALYSTS W.R. GRACE & CO.-CONN. (US) 1996-05-09 WO disclosed
EP-0384398-A1 Cationically electrodepositable paint composition KANSAI PAINT CO., LTD. (JP) 1990-08-29 EP disclosed
EP-0356970-A2 Resin composition for cationically electrodepositable paint KANSAI PAINT CO., LTD. (JP) 1990-03-07 EP disclosed
US-4767796-A STORAGE STABLE LIQUID OF LIQUEFIED METHYLENEBIS(PHENYL ISOCYANATE) AND A CYCLOALKANE DIOL, FOR POLYURETHANES THE DOW CHEMICAL COMPANY (US) 1988-08-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040063764-A1 Halogen compounds having thrombopoietin receptor agonism MPL, TEK, ACKR3 TRIM24 2327/4885TRIM33 4072/4885ALDH1A1 2253/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.