SCHEMBL679754

SCHEMBL679754

C=CC[N]NCC=C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11340134 0.74
SCHEMBL6206070 0.69
SCHEMBL15025230 0.69
SCHEMBL10818640 0.67
SCHEMBL461903 0.67
SCHEMBL6529953 0.67
SCHEMBL9497436 0.67
SCHEMBL2300632 0.67
SCHEMBL2300630 0.67
SCHEMBL7559940 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 267 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4153607-A1 CATIONIC STEROIDAL ANTIMICROBIAL COMPOUNDS WITH ENDOGENOUS GROUPS Brigham Young University (US) 2023-03-29 EP claimed
WO-2021236953-A1 CATIONIC STEROIDAL ANTIMICROBIAL COMPOUNDS WITH ENDOGENOUS GROUPS SAVAGE PAUL B (US) 2021-11-25 WO claimed
US-20210363174-A1 CATIONIC STEROIDAL ANTIMICROBIAL COMPOUNDS WITH ENDOGENOUS GROUPS BRIGHAM YOUNG UNIVERSITY (US) 2021-11-25 US claimed
CN-109651395-A A kind of compound and its preparation method and application targeting degradation FKBP12 and 12.6 中国科学院生物物理研究所 2019-04-19 CN claimed
US-20180280550-A1 CATIONIC STEROID ANTIMICROBIAL DIAGNOSTIC, DETECTION, SCREENING AND IMAGING METHODS BRIGHAM YOUNG UNIVERSITY (US) 2018-10-04 US claimed
US-9867836-B2 Lavage and/or infusion using CSA compounds for increasing fertility in a mammal BRIGHAM YOUNG UNIVERSITY (US) 2018-01-16 US claimed
CN-105777756-A Heteroaryl compound and application thereof in medicines 广东东阳光药业有限公司 2016-07-20 CN claimed
CN-105566321-A Heterarylation compound and application thereof to drugs GUANGDONG HEC PHARMACEUTICAL 2016-05-11 CN claimed
CN-105399698-A Aromatic heterocyclic derivatives and applications of aromatic heterocyclic derivatives in medicines GUANGDONG HEC PHARMACEUTICAL 2016-03-16 CN claimed
US-20150366880-A1 COMPOSITIONS AND METHODS FOR TREATING BONE DISEASES AND BROKEN BONES BRIGHAM YOUNG UNIVERSITY (US) 2015-12-24 US claimed
CN-1105707-C Pyrazole derivative DAIICHI SEIYAKU CO (JP) 2003-04-16 CN claimed
CN-1402729-A Polycycloalkylpurines as adenosine receptor antagonists BIOGEN INC (US) 2003-03-12 CN claimed
CN-1398247-A Colchicol derivatives as vascular damaging agents ANGIOGENE PHARM LTD (GB) 2003-02-19 CN claimed
CN-1342157-A Substituted pyrazoles ASP38 kinase inhibitors SEARLE & CO (US) 2002-03-27 CN claimed
CN-1320122-A Pyrazole derivatives and salts thereof DAIICHI SEIYAKU CO (JP) 2001-10-31 CN claimed
CN-1264377-A Substituted pyrazoles as P38 kinase inhabitors SEARLE & CO (US) 2000-08-23 CN claimed
CN-1251578-A Pyrazole derivative DAIICHI SEIYAKU CO (JP) 2000-04-26 CN claimed
CN-1225634-A Synthesis of indolylmaleimides LILLY CO ELI (US) 1999-08-11 CN claimed
CN-1190963-A 2-amino-benzoxanones for the treatment of viral infections SEARLE & CO (US) 1998-08-19 CN claimed
US-3996407-A PIGMENT, SILANE, BINDER BASF AKTIENGESELLSCHAFT (DT) 1976-12-07 US claimed