SCHEMBL6798288

SCHEMBL6798288

CCCCCC=CCC(C=CC=CCC=CCCCC(=O)O)OO

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OXER1 Q8TDS5 1/20 0.73
MEN1 O00255 2/20 0.65
KMT2A Q03164 2/20 0.65
MAPT P10636 2/20 0.64
LTB4R2 Q9NPC1 1/20 0.64
ALOX5 P09917 1/20 0.64
PPARG P37231 2/20 0.61
KDM4E B2RXH2 1/20 0.61
USP2 O75604 1/20 0.61
ALDH1A1 P00352 1/20 0.61
LMNA P02545 1/20 0.61
TP53 P04637 1/20 0.61
CYP3A4 P08684 1/20 0.61
HSPD1 P10809 1/20 0.61
CYP19A1 P11511 1/20 0.61
FABP4 P15090 1/20 0.61
HPGD P15428 1/20 0.61
ALOX15 P16050 1/20 0.61
CASP1 P29466 1/20 0.61
NR4A2 P43354 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7716313 1.00 OXER1 (0.73) OXER1MEN1KMT2AMAPTLTB4R2
SCHEMBL29688873 1.00 OXER1 (0.73) OXER1MEN1KMT2AMAPTLTB4R2
SCHEMBL6798286 1.00 OXER1 (0.73) OXER1MEN1KMT2AMAPTLTB4R2
SCHEMBL4343443 1.00 OXER1 (0.73) OXER1MEN1KMT2AMAPTLTB4R2
SCHEMBL8025562 1.00 OXER1 (0.73) OXER1MEN1KMT2AMAPTLTB4R2
SCHEMBL2905125 1.00 OXER1 (0.73) OXER1MEN1KMT2AMAPTLTB4R2
SCHEMBL6051176 1.00 OXER1 (0.73) OXER1MEN1KMT2AMAPTLTB4R2
SCHEMBL904542 1.00 OXER1 (0.73) OXER1MEN1KMT2AMAPTLTB4R2
SCHEMBL21213994 1.00 OXER1 (0.73) OXER1MEN1KMT2AMAPTLTB4R2
SCHEMBL4343438 1.00 OXER1 (0.73) OXER1MEN1KMT2AMAPTLTB4R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025015300-A2 HEPOXILIN ANALOGS, METHODS, USES, AND PROCESSES FOR PREPARATION THEREOF APAC PHARMA, LLC (US) 2025-01-16 WO disclosed
EP-4452251-A1 COMPOSITIONS AND METHODS OF USE TO TREAT 12-LIPOXYGENASE (12-LOX) MEDIATED DISEASES Veralox Therapeutics Inc. (US) 2024-10-30 EP disclosed
WO-2023122494-A1 COMPOSITIONS AND METHODS OF USE TO TREAT 12-LIPOXYGENASE (12-LOX) MEDIATED DISEASES VERALOX THERAPEUTICS (US) 2023-06-29 WO disclosed
US-10197498-B2 Compositions and methods for measurement of analytes NORTHEASTERN UNIVERSITY (US) 2019-02-05 US disclosed
US-20160274030-A1 COMPOSITIONS AND METHODS FOR MEASUREMENT OF ANALYTES NORTHEASTERN UNIVERSITY (US) 2016-09-22 US disclosed
US-20040132087-A1 Novel human enzyme family members and uses thereof MILLENNIUM PHARMACEUTICALS, INC. 2004-07-08 US disclosed
US-5260294-A Treatment of diseases caused by oxidative metabolism of arachidonic acid; antiinflammatory, antiallergins, antiarthriric HOFFMAN-LA ROCHE INC. (US) 1993-11-09 US disclosed
US-5191108-A Lipoxygenase inhibitors, antiinflammatory agents HOFFMANN-LA ROCHE INC. (US) 1993-03-02 US disclosed
US-5132310-A Benzochroman compounds, lipoxygenase inhibitors HOFFMANN-LA ROCHE INC. (US) 1992-07-21 US disclosed
US-5025036-A Antiinflammatory agents, gastrointestinal, cardiovascular and skin disorders HOFFMANN-LA ROCHE INC. (US) 1991-06-18 US disclosed
US-5015661-A Lipoxygenase inhibitors HOFFMANN-LA ROCHE INC. (US) 1991-05-14 US disclosed
US-4885309-A FOR PSORIASIS, DERMATITIS, AND ECZEMA HOFFMANN-LA ROCHE INC. (US) 1989-12-05 US disclosed
US-4789745-A Certain 3-[3-(3-pyridinyloxy)propoxy or propylthio]-acetic acid derivatives which are useful as synthetase inhibitors THE UPJOHN COMPANY (US) 1988-12-06 US disclosed
EP-0099685-B1 (3-PYRIDINYL)HETEROALKANOLS AND ALKANOIC ACIDS AND ESTERS THE UPJOHN COMPANY (US) 1988-09-21 EP disclosed
EP-0099685-A2 (3-Pyridinyl)heteroalkanols and alkanoic acids and esters THE UPJOHN COMPANY (US) 1984-02-01 EP disclosed