SCHEMBL679876

SCHEMBL679876

COc1ccc(Oc2ccc(S(=O)(=O)c3ccc(C)cc3)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.73
SMN1; SMN2 Q16637 1/20 0.73
PKM P14618 2/20 0.73
TDP1 Q9NUW8 1/20 0.65
L3MBTL1 Q9Y468 1/20 0.65
GAA P10253 2/20 0.61
RAPGEF4 Q8WZA2 1/20 0.59
ALDH1A1 P00352 3/20 0.58
CYP3A4 P08684 1/20 0.58
CYP2C9 P11712 1/20 0.58
CYP2C19 P33261 1/20 0.58
ACHE P22303 2/20 0.58
BCHE P06276 1/20 0.57
MAPT P10636 1/20 0.50
MMP2 P08253 2/20 0.49
MMP9 P14780 2/20 0.49
MMP8 P22894 2/20 0.49
MMP12 P39900 2/20 0.49
MMP13 P45452 2/20 0.49
MMP14 P50281 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12213201 1.00 HTT (0.73) HTTSMN1; SMN2PKMTDP1L3MBTL1
SCHEMBL17565752 1.00 HTT (0.73) HTTSMN1; SMN2PKMTDP1L3MBTL1
SCHEMBL686310 1.00 HTT (0.73) HTTSMN1; SMN2PKMTDP1L3MBTL1
SCHEMBL10034461 1.00 HTT (0.73) HTTSMN1; SMN2PKMTDP1L3MBTL1
SCHEMBL12120846 1.00 HTT (0.73) HTTSMN1; SMN2PKMTDP1L3MBTL1
SCHEMBL14148710 1.00 HTT (0.73) HTTSMN1; SMN2PKMTDP1L3MBTL1
SCHEMBL10093716 1.00 HTT (0.73) HTTSMN1; SMN2PKMTDP1L3MBTL1
SCHEMBL10093717 1.00 HTT (0.73) HTTSMN1; SMN2PKMTDP1L3MBTL1
SCHEMBL13021059 0.95 HTT (0.67) HTTSMN1; SMN2PKMTDP1L3MBTL1
SCHEMBL12857765 0.95 HTT (0.67) HTTSMN1; SMN2PKMTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 318 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230399468-A1 BIO-BASED SULFONE COPOLYMERS FREE OF BPA AND BPS SYENSQO SPECIALTY POLYMERS USA, LLC 2023-12-14 US disclosed
US-20230399468-A1 BIO-BASED SULFONE COPOLYMERS FREE OF BPA AND BPS SYENSQO SPECIALTY POLYMERS USA, LLC 2023-12-14 US disclosed
US-20230374221-A1 PROCESS FOR THE MANUFACTURE OF SULFONATED POLYARLYENE(ETHER) SULFONES BASF SE (DE) 2023-11-23 US disclosed
EP-3230986-B1 POLY(ARYL ETHER) COMPOSITIONS FOR POLYMER-METAL JUNCTIONS AND POLYMER-METAL JUNCTIONS AND CORRESPONDING FABRICATION METHODS SOLVAY SPECIALTY POLYMERS USA (US) 2023-11-22 EP disclosed
US-20230348696-A1 COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES PREPARED THEREFROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2023-11-02 US disclosed
US-20230348696-A1 COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES PREPARED THEREFROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2023-11-02 US disclosed
EP-4008751-B1 COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES PREPARED THEREFROM SHPP GLOBAL TECH BV (NL) 2023-09-06 EP disclosed
EP-2794128-B1 HIGH PERFORMANCE POLYMER COMPOSITION FOR MOBILE ELECTRONIC DEVICES SOLVAY SPECIALTY POLYMERS USA (US) 2023-05-03 EP disclosed
EP-3389877-B1 MULTILAYER ASSEMBLY SOLVAY SPECIALTY POLYMERS IT (IT) 2023-04-26 EP disclosed
US-11565217-B2 Composition and method for manufacturing sulfone polymer membrane SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2023-01-31 US disclosed
US-20080051514-A1 Polysulfone-Polyether Blockcopolymers, Process To Synthesize It, Membranes Made Therefrom SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2008-02-28 US disclosed
US-20070281195-A1 Block copolymer and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED 2007-12-06 US disclosed
US-20070276100-A1 Electronic Components SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2007-11-29 US disclosed
US-20070276100-A1 Electronic Components SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2007-11-29 US disclosed
EP-1854846-A1 Polymer blends comprising a polysulfone and a modified polyolefin, and methods for their preparation SOLVAY SPECIALITIES INDIA PRIVATE LIMITED (IN) 2007-11-14 EP disclosed
EP-1538183-B1 THERMOPLASTIC FILM, THERMOPLASTIC RESIN COMPOSITION, AND PHYLLOSILICATE TEIJIN LTD (JP) 2007-10-31 EP disclosed
US-20070166591-A1 POLYMER ELECTROLYTE COMPOSITION AND APPLICATION THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-07-19 US disclosed
US-7229580-B2 blending a polyphenylene oxide or polysulfone with a polyimide by selectively decomposing the polyimide phase using monoethanolamine or tetramethylammonium hydroxide; narrow pore size distribution; makes membranes for fluid separations, such as microfiltration, ultrafiltration, and gas separation POROGEN CORPORATION (US) 2007-06-12 US disclosed
US-20070066759-A1 Block copolymers and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-03-22 US disclosed
US-7189782-B2 Thermoplastic film, thermoplastic resin composition, and phyllosilicate TEIJIN LIMITED (JP) 2007-03-13 US disclosed