Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B17 | O75795 | 2/20 | 1.00 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.33 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1508636 | 0.90 | UGT2B17 (0.82) | UGT2B17KDM4CSIGMAR1TAS1R3TAS1R1 | |
| SCHEMBL10286363 | 0.84 | UGT2B17 (0.72) | UGT2B17TAS1R3TAS1R1TAS1R2CYP11B1 | |
| SCHEMBL22222496 | 0.78 | UGT2B17 (0.64) | UGT2B17KDM4CSIGMAR1PSMB5 | |
| SCHEMBL5272877 | 0.77 | UGT2B17 (0.62) | UGT2B17KDM4CSIGMAR1TAS1R3TAS1R1 | |
| SCHEMBL703510 | 0.77 | UGT2B17 (0.62) | UGT2B17KDM4CSIGMAR1TAS1R3TAS1R1 | |
| SCHEMBL30831935 | 0.77 | UGT2B17 (0.62) | UGT2B17KDM4CSIGMAR1TAS1R3TAS1R1 | |
| SCHEMBL15286569 | 0.77 | UGT2B17 (0.62) | UGT2B17KDM4CSIGMAR1GAA | |
| Hydrochloric Acid SCHEMBL1976240 | 0.76 | UGT2B17 (0.61) | UGT2B17KDM4CSIGMAR1TAS1R3TAS1R1 | |
| SCHEMBL5173559 | 0.75 | UGT2B17 (0.60) | UGT2B17KDM4CSIGMAR1CYP11B1CYP11B2 | |
| SCHEMBL12014020 | 0.73 | UGT2B17 (0.58) | UGT2B17TAS1R3TAS1R1TAS1R2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6750243-B1 | COMPETITIVE INHIBITORS OF TRYPSIN-LIKE SERINE PROTEASES, ESPECIALLY THROMBIN; chemical synthesis; anticoagulants; treatment of thrombosis | AstraZeneća AB (SE) | 2004-06-15 | — | — | US | claimed |