SCHEMBL6799565

SCHEMBL6799565

NC1(C(=O)O)CC(NC(=O)Nc2ccc(Cl)cc2)C2C(C(=O)O)C21

nearest known ligand 0.71

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 19/20 0.71
GRM3 Q14832 19/20 0.71
GRM6 O15303 3/20 0.56
GRM8 O00222 1/20 0.56
GRM4 Q14833 1/20 0.49
CNR1 P21554 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6797937 1.00 GRM2 (0.71) GRM2GRM3GRM6GRM8GRM4
SCHEMBL6796401 0.89 GRM2 (0.70) GRM2GRM3GRM6GRM8GRM4
SCHEMBL6789067 0.89 GRM2 (0.60) GRM2GRM3GRM6GRM8GRM4
SCHEMBL6796653 0.88 GRM2 (0.61) GRM2GRM3GRM6GRM8GRM4
SCHEMBL6795258 0.88 GRM2 (0.61) GRM2GRM3GRM6GRM8GRM4
SCHEMBL6792837 0.88 GRM2 (0.71) GRM2GRM3GRM6GRM8GRM4
SCHEMBL6795022 0.88 GRM2 (0.60) GRM2GRM3GRM6GRM8GRM4
SCHEMBL6790536 0.88 GRM2 (0.72) GRM2GRM3GRM6GRM8GRM4
SCHEMBL6788529 0.88 GRM2 (0.72) GRM2GRM3GRM6GRM8GRM4
SCHEMBL6795308 0.85 GRM2 (0.73) GRM2GRM3GRM6GRM8GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040116489-A1 Synthetic excitatory amino acids ELI LILLY AND COMPANY 2004-06-17 US disclosed