Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 6/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 6/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 6/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 6/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 6/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7563524 | 0.77 | MCL1 (0.36) | — | |
| SCHEMBL6804436 | 0.76 | KMT2A (0.49) | ALDH1A1MAPTTDP1KMT2AHTT | |
| SCHEMBL6802953 | 0.75 | CCR4 (0.38) | — | |
| SCHEMBL6800094 | 0.74 | — | — | |
| SCHEMBL6801536 | 0.72 | PSEN1 (0.42) | ALDH1A1MAPTTDP1KMT2AHTT | |
| SCHEMBL682128 | 0.71 | MAPT (0.63) | ALDH1A1MAPTTDP1KMT2AHTT | |
| SCHEMBL22115699 | 0.71 | CYP1A2 (0.47) | ALDH1A1MAPTTDP1KMT2AHTT | |
| SCHEMBL6802725 | 0.70 | KMT2A (0.66) | ALDH1A1MAPTTDP1KMT2AHTT | |
| SCHEMBL194745 | 0.70 | MAPT (0.53) | ALDH1A1MAPTTDP1KMT2AHTT | |
| SCHEMBL6798127 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040010142-A1 | Novel process | NOVO NORDISK A/S (DK) | 2004-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040010142-A1 | Novel process | UGT1A1, CYP4X1, CYP4B1 | ALDH1A1 146/4885MAPT 3454/4885TDP1 3187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.