Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 3/20 | 0.79 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.70 |
| ▸ | TUBB | P07437 | 1/20 | 0.70 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.70 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.70 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.70 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.70 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.70 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.70 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.70 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.70 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.70 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.70 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.70 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.70 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.70 |
| ▸ | NQO1 | P15559 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL847531 | 1.00 | NQO2 (0.79) | NQO2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL847532 | 1.00 | NQO2 (0.79) | NQO2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9862507 | 1.00 | NQO2 (0.79) | NQO2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL847533 | 1.00 | NQO2 (0.79) | NQO2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6801712 | 1.00 | NQO2 (0.79) | NQO2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9390654 | 0.92 | NQO2 (0.68) | NQO2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9789488 | 0.92 | NQO2 (0.68) | NQO2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9789494 | 0.92 | NQO2 (0.68) | NQO2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9390649 | 0.92 | NQO2 (0.68) | NQO2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9789491 | 0.92 | NQO2 (0.68) | NQO2TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11622954-B2 | Estrogen receptor ligands, compositions and methods related thereto | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-04-11 | — | — | US | disclosed |
| US-20210196667-A1 | ESTROGEN RECEPTOR LIGANDS, COMPOSITIONS AND METHODS RELATED THERETO | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2021-07-01 | — | — | US | disclosed |
| EP-3509583-B1 | ESTROGEN RECEPTOR LIGANDS, COMPOSITIONS AND METHODS RELATED THERETO | UNIV CALIFORNIA (US) | 2021-06-30 | — | — | EP | disclosed |
| US-10980767-B2 | Estrogen receptor ligands, compositions and methods related thereto | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-04-20 | — | — | US | disclosed |
| US-20190192476-A1 | ESTROGEN RECEPTOR LIGANDS, COMPOSITIONS AND METHODS RELATED THERETO | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-06-27 | — | — | US | disclosed |
| CN-109535030-A | It is a kind of using formamide as the preparation method of the acrylonitrile compound in cyanogen source | 湘潭大学 | 2019-03-29 | — | — | CN | disclosed |
| WO-2018049094-A1 | ESTROGEN RECEPTOR LIGANDS, COMPOSITIONS AND METHODS RELATED THERETO | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-03-15 | — | — | WO | disclosed |
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190192476-A1 | ESTROGEN RECEPTOR LIGANDS, COMPOSITIONS AND METHODS RELATED THERETO | ESR2, ESRRG, ESR1 | NQO2 3144/4885TUBB4A 1061/4885TUBB 1018/4885 |
| US-20210196667-A1 | ESTROGEN RECEPTOR LIGANDS, COMPOSITIONS AND METHODS RELATED THERETO | ESR2, ESRRG, ESR1 | NQO2 3144/4885TUBB4A 1061/4885TUBB 1018/4885 |
| US-11622954-B2 | Estrogen receptor ligands, compositions and methods related thereto | ESR2, ESRRG, ESR1 | NQO2 3144/4885TUBB4A 1061/4885TUBB 1018/4885 |
| US-10980767-B2 | Estrogen receptor ligands, compositions and methods related thereto | ESR2, ESRRG, ESR1 | NQO2 3144/4885TUBB4A 1061/4885TUBB 1018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.